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Functional Pathway Analysis Using SCNP of FLT3 Receptor Pathway Deregulation in AML Provides Prognostic Information Independent from Mutational Status

FMS-like tyrosine kinase 3 receptor (FLT3) internal tandem duplication (ITD) mutations result in constitutive activation of this receptor and have been shown to increase the risk of relapse in patients with acute myeloid leukemia (AML); however, substantial heterogeneity in clinical outcomes still e...

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Detalhes bibliográficos
Main Authors: Cesano, Alessandra, Putta, Santosh, Rosen, David B., Cohen, Aileen C., Gayko, Urte, Mathi, Kavita, Woronicz, John, Hawtin, Rachael E., Cripe, Larry, Sun, Zhuoxin, Tallman, Martin S., Paietta, Elisabeth
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576376/
https://ncbi.nlm.nih.gov/pubmed/23431389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056714
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