Genomic characterization of pediatric T-cell acute lymphoblastic leukemia reveals novel recurrent driver mutations

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematologic malignancy with variable prognosis. It represents 15% of diagnosed pediatric ALL cases and has a threefold higher incidence among males. Many recurrent alterations have been identified and help define molecular subgroups of T-A...

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Vydáno v:Oncotarget
Hlavní autoři: Spinella, Jean-François, Cassart, Pauline, Richer, Chantal, Saillour, Virginie, Ouimet, Manon, Langlois, Sylvie, St-Onge, Pascal, Sontag, Thomas, Healy, Jasmine, Minden, Mark D., Sinnett, Daniel
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323170/
https://ncbi.nlm.nih.gov/pubmed/27602765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11796
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