A novel somatic mutation in ACD induces telomere lengthening and apoptosis resistance in leukemia cells

BACKGROUND: The identification of oncogenic driver mutations has largely relied on the assumption that genes that exhibit more mutations than expected by chance are more likely to play an active role in tumorigenesis. Major cancer sequencing initiatives have therefore focused on recurrent mutations...

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Dettagli Bibliografici
Pubblicato in:BMC Cancer
Autori principali: Spinella, Jean-François, Cassart, Pauline, Garnier, Nicolas, Rousseau, Philippe, Drullion, Claire, Richer, Chantal, Ouimet, Manon, Saillour, Virginie, Healy, Jasmine, Autexier, Chantal, Sinnett, Daniel
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562123/
https://ncbi.nlm.nih.gov/pubmed/26345285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1639-5
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