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Mutational dynamics of early and late relapsed childhood ALL: rapid clonal expansion and long-term dormancy

Childhood acute lymphoblastic leukemia (cALL) is the most frequent pediatric cancer. Refractory/relapsed cALL presents a survival rate of ∼45% and is still one of the leading causes of death by disease among children. Mechanisms, such as clonal competition and evolutionary adaptation, govern treatme...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Blood Adv
Egile Nagusiak: Spinella, Jean-François, Richer, Chantal, Cassart, Pauline, Ouimet, Manon, Healy, Jasmine, Sinnett, Daniel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5812325/
https://ncbi.nlm.nih.gov/pubmed/29365312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017011510
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