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Mutational dynamics of early and late relapsed childhood ALL: rapid clonal expansion and long-term dormancy
Childhood acute lymphoblastic leukemia (cALL) is the most frequent pediatric cancer. Refractory/relapsed cALL presents a survival rate of ∼45% and is still one of the leading causes of death by disease among children. Mechanisms, such as clonal competition and evolutionary adaptation, govern treatme...
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| Publicat a: | Blood Adv |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society of Hematology
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5812325/ https://ncbi.nlm.nih.gov/pubmed/29365312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017011510 |
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