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Joint genotype inference with germline and somatic mutations

The joint sequencing of related genomes has become an important means to discover rare variants. Normal-tumor genome pairs are routinely sequenced together to find somatic mutations and their associations with different cancers. Parental and sibling genomes reveal de novo germline mutations and inhe...

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Detalhes bibliográficos
Main Authors: Bareke, Eric, Saillour, Virginie, Spinella, Jean-François, Vidal, Ramon, Healy, Jasmine, Sinnett, Daniel, Csűrös, Miklós
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622648/
https://ncbi.nlm.nih.gov/pubmed/23734724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-S5-S3
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