Metabolic Adaptation to Chronic Inhibition of Mitochondrial Protein Synthesis in Acute Myeloid Leukemia Cells

Por Jhas, Bozhena, Sriskanthadevan, Shrivani, Skrtic, Marko, Sukhai, Mahadeo A., Voisin, Veronique, Jitkova, Yulia, Gronda, Marcela, Hurren, Rose, Laister, Rob C., Bader, Gary D., Minden, Mark D., Schimmer, Aaron D.
Publicado em 2013

The ubiquitin-activating enzyme E1 as a therapeutic target for the treatment of leukemia and multiple myeloma

Por Xu, G. Wei, Ali, Mohsin, Wood, Tabitha E., Wong, Derek, Maclean, Neil, Wang, Xiaoming, Gronda, Marcela, Skrtic, Marko, Li, Xiaoming, Hurren, Rose, Mao, Xinliang, Venkatesan, Meenakshi, Zavareh, Reza Beheshti, Ketela, Troy, Reed, John C., Rose, David, Moffat, Jason, Batey, Robert A., Dhe-Paganon, Sirano, Schimmer, Aaron D.
Publicado em 2010

AML cells have low spare reserve capacity in their respiratory chain that renders them susceptible to oxidative metabolic stress

Por Sriskanthadevan, Shrivani, Jeyaraju, Danny V., Chung, Timothy E., Prabha, Swayam, Xu, Wei, Skrtic, Marko, Jhas, Bozhena, Hurren, Rose, Gronda, Marcela, Wang, Xiaoming, Jitkova, Yulia, Sukhai, Mahadeo A., Lin, Feng-Hsu, Maclean, Neil, Laister, Rob, Goard, Carolyn A., Mullen, Peter J., Xie, Stephanie, Penn, Linda Z., Rogers, Ian M., Dick, John E., Minden, Mark D., Schimmer, Aaron D.
Publicado no Blood (2015)

INHIBITION OF MITOCHONDRIAL TRANSLATION AS A THERAPEUTIC STRATEGY FOR HUMAN ACUTE MYELOID LEUKEMIA

Por Škrtić, Marko, Sriskanthadevan, Shrivani, Jhas, Bozhena, Gebbia, Marinella, Wang, Xiaoming, Wang, Zezhou, Hurren, Rose, Jitkova, Yulia, Gronda, Marcela, Maclean, Neil, Lai, Courteney K., Eberhard, Yanina, Bartoszko, Justyna, Spagnuolo, Paul, Rutledge, Angela C., Datti, Alessandro, Ketela, Troy, Moffat, Jason, Robinson, Brian H., Cameron, Jessie H., Wrana, Jeffery, Eaves, Connie J., Minden, Mark D., Wang, Jean C.Y., Dick, John E., Humphries, Keith, Nislow, Corey, Giaever, Guri, Schimmer, Aaron D.
Publicado em 2011

Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors

Por Sukhai, Mahadeo A., Prabha, Swayam, Hurren, Rose, Rutledge, Angela C., Lee, Anna Y., Sriskanthadevan, Shrivani, Sun, Hong, Wang, Xiaoming, Skrtic, Marko, Seneviratne, Ayesh, Cusimano, Maria, Jhas, Bozhena, Gronda, Marcela, MacLean, Neil, Cho, Eunice E., Spagnuolo, Paul A., Sharmeen, Sumaiya, Gebbia, Marinella, Urbanus, Malene, Eppert, Kolja, Dissanayake, Dilan, Jonet, Alexia, Dassonville-Klimpt, Alexandra, Li, Xiaoming, Datti, Alessandro, Ohashi, Pamela S., Wrana, Jeff, Rogers, Ian, Sonnet, Pascal, Ellis, William Y., Corey, Seth J., Eaves, Connie, Minden, Mark D., Wang, Jean C.Y., Dick, John E., Nislow, Corey, Giaever, Guri, Schimmer, Aaron D.
Publicado em 2012