Anti leukemia effect of ex vivo expanded DNT cells from AML patients: a potential novel autologous T cell adoptive immunotherapy

CD3(+)CD56(−), CD4 and CD8 double negative T (DNT) cells comprise 1–3% of peripheral blood mononuclear cells. Their role in tumor immunity remains largely unknown due to their limited numbers and lack of effective methods to expand them. Here we developed a novel protocol by which DNT cells can be e...

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Detalhes bibliográficos
Main Authors: Merims, Sharon, Li, Xujian, Joe, Betty, Dokouhaki, Pouneh, Han, Mei, Childs, Richard W., Wang, Zhen-yi, Gupta, Vikas, Minden, Mark D., Zhang, Li
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4214360/
https://ncbi.nlm.nih.gov/pubmed/21566657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2011.99
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