Deletion of MCP-1 Impedes Pathogenesis of Acid Ceramidase Deficiency

Por Yu, Fabian P. S., Dworski, Shaalee, Medin, Jeffrey A.
Publicado no Sci Rep (2018)

Relative distribution of Gb(3) isoforms/analogs in NOD/SCID/Fabry mice tissues determined by tandem mass spectrometry

Por Provençal, Philippe, Boutin, Michel, Dworski, Shaalee, Au, Bryan, Medin, Jeffrey A, Auray-Blais, Christiane
Publicado no Bioanalysis (2016)

Pathologic Bladder Microenvironment Attenuates Smooth Muscle Differentiation of Skin Derived Precursor Cells: Implications for Tissue Regeneration

Por Tolg, Cornelia, Ahsan, Alya, Dworski, Shaalee, Kirwan, Tyler, Yu, Jeffery, Aitken, Karen, Bägli, Darius Jehan
Publicado em 2013

Enzyme replacement therapy for Farber disease: Proof-of-concept studies in cells and mice

Por He, Xingxuan, Dworski, Shaalee, Zhu, Changzhi, DeAngelis, Victor, Solyom, Alex, Medin, Jeffrey A., Simonaro, Calogera M., Schuchman, Edward H.
Publicado no BBA Clin (2017)

Markedly perturbed hematopoiesis in acid ceramidase deficient mice

Por Dworski, Shaalee, Berger, Alexandra, Furlonger, Caren, Moreau, Joshua M., Yoshimitsu, Makoto, Trentadue, Jessa, Au, Bryan C.Y., Paige, Christopher J., Medin, Jeffrey A.
Publicado no Haematologica (2015)

Transplantation of Skin Precursor-Derived Schwann Cells Yields Better Locomotor Outcomes and Reduces Bladder Pathology in Rats with Chronic Spinal Cord Injury

Por Assinck, Peggy, Sparling, Joseph S., Dworski, Shaalee, Duncan, Greg J., Wu, Di L., Liu, Jie, Kwon, Brian K., Biernaskie, Jeff, Miller, Freda D., Tetzlaff, Wolfram
Publicado no Stem Cell Reports (2020)

On-Tissue Localization of Ceramides and Other Sphingolipids by MALDI Mass Spectrometry Imaging

Por Jones, E. Ellen, Dworski, Shaalee, Canals, Daniel, Casas, Josefina, Fabrias, Gemma, Schoenling, Drew, Levade, Thierry, Denlinger, Chadrick, Hannun, Yusuf A., Medin, Jeffrey A., Drake, Richard R.
Publicado em 2014

Chronic lung injury and impaired pulmonary function in a mouse model of acid ceramidase deficiency

Por Yu, Fabian P. S., Islam, Diana, Sikora, Jakub, Dworski, Shaalee, Gurka, Jiří, López-Vásquez, Lucía, Liu, Mingyao, Kuebler, Wolfgang M., Levade, Thierry, Zhang, Haibo, Medin, Jeffrey A.
Publicado no Am J Physiol Lung Cell Mol Physiol (2018)

Direct Genesis of Functional Rodent and Human Schwann Cells from Skin Mesenchymal Precursors

Por Krause, Matthew P., Dworski, Shaalee, Feinberg, Konstantin, Jones, Karen, Johnston, Adam P.W., Paul, Smitha, Paris, Maryline, Peles, Elior, Bagli, Darius, Forrest, Christopher R., Kaplan, David R., Miller, Freda D.
Publicado em 2014

Acid Ceramidase Deficiency in Mice Results in a Broad Range of Central Nervous System Abnormalities

Por Sikora, Jakub, Dworski, Shaalee, Jones, E. Ellen, Kamani, Mustafa A., Micsenyi, Matthew C., Sawada, Tomo, Le Faouder, Pauline, Bertrand-Michel, Justine, Dupuy, Aude, Dunn, Christopher K., Xuan, Ingrid Cong Yang, Casas, Josefina, Fabrias, Gemma, Hampson, David R., Levade, Thierry, Drake, Richard R., Medin, Jeffrey A., Walkley, Steven U.
Publicado no Am J Pathol (2017)

Systemic ceramide accumulation leads to severe and varied pathological consequences

Por Alayoubi, Abdulfatah M, Wang, James C M, Au, Bryan C Y, Carpentier, Stéphane, Garcia, Virginie, Dworski, Shaalee, El-Ghamrasni, Samah, Kirouac, Kevin N, Exertier, Mathilde J, Xiong, Zi Jian, Privé, Gilbert G, Simonaro, Calogera M, Casas, Josefina, Fabrias, Gemma, Schuchman, Edward H, Turner, Patricia V, Hakem, Razqallah, Levade, Thierry, Medin, Jeffrey A
Publicado em 2013

Lentivector Iterations and Pre-Clinical Scale-Up/Toxicity Testing: Targeting Mobilized CD34(+) Cells for Correction of Fabry Disease

Por Huang, Ju, Khan, Aneal, Au, Bryan C., Barber, Dwayne L., López-Vásquez, Lucía, Prokopishyn, Nicole L., Boutin, Michel, Rothe, Michael, Rip, Jack W., Abaoui, Mona, Nagree, Murtaza S., Dworski, Shaalee, Schambach, Axel, Keating, Armand, West, Michael L., Klassen, John, Turner, Patricia V., Sirrs, Sandra, Rupar, C. Anthony, Auray-Blais, Christiane, Foley, Ronan, Medin, Jeffrey A.
Publicado no Mol Ther Methods Clin Dev (2017)

Acid Ceramidase Deficiency is Characterized by a Unique Plasma Cytokine and Ceramide Profile that is Altered by Therapy

Por Dworski, Shaalee, Lu, Ping, Khan, Aneal, Maranda, Bruno, Mitchell, John J., Parini, Rossella, Di Rocco, Maja, Hugle, Boris, Yoshimitsu, Makoto, Magnusson, Bo, Makay, Balahan, Arslan, Nur, Guelbert, Norberto, Ehlert, Karoline, Jarisch, Andrea, Gardner-Medwin, Janet, Dagher, Rawane, Terreri, Maria Teresa, Lorenco, Charles Marques, Barillas-Arias, Lilianna, Tanpaiboon, Pranoot, Solyom, Alexander, Norris, James S., He, Xingxuan, Schuchman, Edward H., Levade, Thierry, Medin, Jeffrey A.
Publicado no Biochim Biophys Acta Mol Basis Dis (2016)