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Transplantation of Skin Precursor-Derived Schwann Cells Yields Better Locomotor Outcomes and Reduces Bladder Pathology in Rats with Chronic Spinal Cord Injury

Cell transplantation for spinal cord injury (SCI) has largely been studied in sub-acute settings within 1–2 weeks of injury. In contrast, here we transplanted skin-derived precursors differentiated into Schwann cells (SKP-SCs) into the contused rat spinal cord 8 weeks post-injury (wpi). Twenty-one w...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Assinck, Peggy, Sparling, Joseph S., Dworski, Shaalee, Duncan, Greg J., Wu, Di L., Liu, Jie, Kwon, Brian K., Biernaskie, Jeff, Miller, Freda D., Tetzlaff, Wolfram
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363874/
https://ncbi.nlm.nih.gov/pubmed/32559459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.05.017
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