On-Tissue Localization of Ceramides and Other Sphingolipids by MALDI Mass Spectrometry Imaging

[Image: see text] A novel MALDI-FTICR imaging mass spectrometry (MALDI-IMS) workflow is described for on-tissue detection, spatial localization, and structural confirmation of low abundance bioactive ceramides and other sphingolipids. Increasingly, altered or elevated levels of sphingolipids, sphing...

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Bibliografiske detaljer
Main Authors: Jones, E. Ellen, Dworski, Shaalee, Canals, Daniel, Casas, Josefina, Fabrias, Gemma, Schoenling, Drew, Levade, Thierry, Denlinger, Chadrick, Hannun, Yusuf A., Medin, Jeffrey A., Drake, Richard R.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2014
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139181/
https://ncbi.nlm.nih.gov/pubmed/25072097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac501937d
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