Novel Chemotherapeutic Drugs in Sphingolipid Cancer Research

Por Canals, Daniel, Hannun, Yusuf A.
Publicado em 2013

Protein Phosphatase 1α Mediates Ceramide-induced ERM Protein Dephosphorylation: A NOVEL MECHANISM INDEPENDENT OF PHOSPHATIDYLINOSITOL 4, 5-BIPHOSPHATE (PIP(2)) AND MYOSIN/ERM PHOSP...

Por Canals, Daniel, Roddy, Patrick, Hannun, Yusuf A.
Publicado em 2012

Roles and Regulation of Secretory and Lysosomal Acid Sphingomyelinase

Por Jenkins, Russell W., Canals, Daniel, Hannun, Yusuf A.
Publicado em 2009

Sphingolipid regulation of ezrin, radixin, and moesin protein families: implications for cell dynamics(,)

Por Adada, Mohamad, Canals, Daniel, Hannun, Yusuf A., Obeid, Lina M.
Publicado em 2013

Sphingosine-1-phosphate receptor 2

Por Adada, Mohamad, Canals, Daniel, Hannun, Yusuf A., Obeid, Lina M.
Publicado no FEBS J (2013)

Drug targeting of sphingolipid metabolism: sphingomyelinases and ceramidases

Por Canals, Daniel, Perry, David M, Jenkins, Russell W, Hannun, Yusuf A
Publicado em 2011

Anterograde and retrograde transport of neutral sphingomyelinase-2 between the Golgi and the plasma membrane

Por Milhas, Delphine, Clarke, Christopher J., Idkowiak-Baldys, Jolanta, Canals, Daniel, Hannun, Yusuf A.
Publicado em 2010

CERAMIDE AND SPHINGOSINE-1-PHOSPHATE ACT AS PHOTODYNAMIC THERAPY-ELICITED DAMAGE-ASSOCIATED MOLECULAR PATTERNS: CELL SURFACE EXPOSURE

Por Korbelik, Mladen, Banáth, Judit, Sun, Jinghai, Canals, Daniel, Hannun, Yusuf A., Separovic, Duska
Publicado em 2014

Sphingolipids in Mitochondria

Por Hernández-Corbacho, María José, Salama, Mohamed F., Canals, Daniel, Senkal, Can E., Obeid, Lina M.
Publicado no Biochim Biophys Acta (2016)

Differential Effects of Ceramide and Sphingosine 1-Phosphate on ERM Phosphorylation: PROBING SPHINGOLIPID SIGNALING AT THE OUTER PLASMA MEMBRANE

Por Canals, Daniel, Jenkins, Russell W., Roddy, Patrick, Hernández-Corbacho, María José, Obeid, Lina M., Hannun, Yusuf A.
Publicado em 2010

Critical determinants of mitochondria-associated neutral sphingomyelinase (MA-nSMase) for mitochondrial localization

Por Rajagopalan, Vinodh, Canals, Daniel, Luberto, Chiara, Snider, Justin, Voelkel-Johnson, Christina, Obeid, Lina M., Hannun, Yusuf A
Publicado no Biochim Biophys Acta (2014)

Epidermal growth factor-induced cellular invasion requires sphingosine-1-phosphate/sphingosine-1-phosphate 2 receptor-mediated ezrin activation

Por Orr Gandy, K. Alexa, Adada, Mohamad, Canals, Daniel, Carroll, Brittany, Roddy, Patrick, Hannun, Yusuf A., Obeid, Lina M.
Publicado em 2013

A Novel Mechanism of Lysosomal Acid Sphingomyelinase Maturation: REQUIREMENT FOR CARBOXYL-TERMINAL PROTEOLYTIC PROCESSING

Por Jenkins, Russell W., Idkowiak-Baldys, Jolanta, Simbari, Fabio, Canals, Daniel, Roddy, Patrick, Riner, Clarke D., Clarke, Christopher J., Hannun, Yusuf A.
Publicado em 2011

Sphingosine 1-Phosphate induces filopodia formation through S1P2R activation of ERM proteins

Por Gandy, K. Alexa Orr, Canals, Daniel, Adada, Mohamad, Wada, Masayuki, Roddy, Patrick, Snider, Ashley J., Hannun, Yusuf A., Obeid, Lina M.
Publicado em 2013

Sphingosine Kinase 1 Regulates Tumor Necrosis Factor-mediated RANTES Induction through p38 Mitogen-activated Protein Kinase but Independently of Nuclear Factor κB Activation

Por Adada, Mohamad M., Orr-Gandy, K. Alexa, Snider, Ashley J., Canals, Daniel, Hannun, Yusuf A., Obeid, Lina M., Clarke, Christopher J.
Publicado em 2013

Regulated Secretion of Acid Sphingomyelinase: IMPLICATIONS FOR SELECTIVITY OF CERAMIDE FORMATION

Por Jenkins, Russell W., Canals, Daniel, Idkowiak-Baldys, Jolanta, Simbari, Fabio, Roddy, Patrick, Perry, David M., Kitatani, Kazuyuki, Luberto, Chiara, Hannun, Yusuf A.
Publicado em 2010

On-Tissue Localization of Ceramides and Other Sphingolipids by MALDI Mass Spectrometry Imaging

Por Jones, E. Ellen, Dworski, Shaalee, Canals, Daniel, Casas, Josefina, Fabrias, Gemma, Schoenling, Drew, Levade, Thierry, Denlinger, Chadrick, Hannun, Yusuf A., Medin, Jeffrey A., Drake, Richard R.
Publicado em 2014

Intracellular sphingosine kinase 2–derived sphingosine-1-phosphate mediates epidermal growth factor–induced ezrin-radixin-moesin phosphorylation and cancer cell invasion

Por Adada, Mohamad M., Canals, Daniel, Jeong, Nara, Kelkar, Ashwin D., Hernandez-Corbacho, Maria, Pulkoski-Gross, Michael J., Donaldson, Jane C., Hannun, Yusuf A., Obeid, Lina M.
Publicado no FASEB J (2015)

Tumor Necrosis Factor-α (TNFα)-induced Ceramide Generation via Ceramide Synthases Regulates Loss of Focal Adhesion Kinase (FAK) and Programmed Cell Death

Por Hernández-Corbacho, María José, Canals, Daniel, Adada, Mohamad M., Liu, Mengling, Senkal, Can E., Yi, Jae Kyo, Mao, Cungui, Luberto, Chiara, Hannun, Yusuf A., Obeid, Lina M.
Publicado no J Biol Chem (2015)

Activity of neutral and alkaline ceramidases on fluorogenic N-acylated coumarin-containing aminodiols

Por Casasampere, Mireia, Camacho, Luz, Cingolani, Francesca, Casas, Josefina, Egido-Gabás, Meritxell, Abad, José Luís, Bedia, Carmen, Xu, Ruijuan, Wang, Kai, Canals, Daniel, Hannun, Yusuf A., Mao, Cungui, Fabrias, Gemma
Publicado no J Lipid Res (2015)