Deficiency of the alkaline ceramidase ACER3 manifests in early childhood by progressive leukodystrophy

Por Edvardson, Simon, Yi, Jae Kyo, Jalas, Chaim, Xu, Ruijuan, Webb, Bryn D, Snider, Justin, Fedick, Anastasia, Kleinman, Elisheva, Treff, Nathan R, Mao, Cungui, Elpeleg, Orly
Publicado no J Med Genet (2016)

Tumor Necrosis Factor-α (TNFα)-induced Ceramide Generation via Ceramide Synthases Regulates Loss of Focal Adhesion Kinase (FAK) and Programmed Cell Death

Por Hernández-Corbacho, María José, Canals, Daniel, Adada, Mohamad M., Liu, Mengling, Senkal, Can E., Yi, Jae Kyo, Mao, Cungui, Luberto, Chiara, Hannun, Yusuf A., Obeid, Lina M.
Publicado no J Biol Chem (2015)

Aging-related elevation of sphingoid bases shortens yeast chronological life span by compromising mitochondrial function

Por Yi, Jae Kyo, Xu, Ruijuan, Jeong, Eunmi, Mileva, Izolda, Truman, Jean-Philip, Lin, Chih-li, Wang, Kai, Snider, Justin, Wen, Sally, Obeid, Lina M., Hannun, Yusuf A., Mao, Cungui
Publicado no Oncotarget (2016)

Phosphorylation of p90RSK is associated with increased response to neoadjuvant chemotherapy in ER-positive breast cancer

Por Moon, Hyeong-Gon, Yi, Jae Kyo, Kim, Hee Sung, Lee, Hea Young, Lee, Kyung-Min, Yi, Minju, Ahn, Sookyung, Shin, Hee-Chul, Ju, Ji-hyun, Shin, Incheol, Han, Wonshik, Noh, Dong-Young
Publicado em 2012

Tricyclic Antidepressants Promote Ceramide Accumulation to Regulate Collagen Production in Human Hepatic Stellate Cells

Por Chen, Jennifer Y., Newcomb, Benjamin, Zhou, Chan, Pondick, Joshua V., Ghoshal, Sarani, York, Samuel R., Motola, Daniel L., Coant, Nicolas, Yi, Jae Kyo, Mao, Cungui, Tanabe, Kenneth K., Bronova, Irina, Berdyshev, Evgeny V., Fuchs, Bryan C., Hannun, Yusuf, Chung, Raymond T., Mullen, Alan C.
Publicado no Sci Rep (2017)

Alkaline Ceramidase 3 Deficiency Results in Purkinje Cell Degeneration and Cerebellar Ataxia Due to Dyshomeostasis of Sphingolipids in the Brain

Por Wang, Kai, Xu, Ruijuan, Schrandt, Jennifer, Shah, Prithvi, Gong, Yong Z., Preston, Chet, Wang, Louis, Yi, Jae Kyo, Lin, Chih-Li, Sun, Wei, Spyropoulos, Demetri D., Rhee, Soyoung, Li, Mingsong, Zhou, Jie, Ge, Shaoyu, Zhang, Guofeng, Snider, Ashley J., Hannun, Yusuf A., Obeid, Lina M., Mao, Cungui
Publicado no PLoS Genet (2015)