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Roles and Regulation of Secretory and Lysosomal Acid Sphingomyelinase

Acid sphingomyelinase occupies a prominent position in sphingolipid catabolism, catalyzing the hydrolysis of sphingomyelin to ceramide and phosphorylcholine. Enzymatic dysfunction of acid sphingomyelinase results in Niemann-Pick disease, a lysosomal storage disorder characterized at the cellular lev...

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Sonraí Bibleagrafaíochta
Main Authors: Jenkins, Russell W., Canals, Daniel, Hannun, Yusuf A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488588/
https://ncbi.nlm.nih.gov/pubmed/19385042
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