Synergistic Interaction of Rnf8 and p53 in the Protection against Genomic Instability and Tumorigenesis

Por Halaby, Marie-Jo, Hakem, Anne, Li, Li, El Ghamrasni, Samah, Venkatesan, Shriram, Hande, Prakash M., Sanchez, Otto, Hakem, Razqallah
Publicado em 2013

Rnf8 deficiency impairs class switch recombination, spermatogenesis, and genomic integrity and predisposes for cancer

Por Li, Li, Halaby, Marie-Jo, Hakem, Anne, Cardoso, Renato, El Ghamrasni, Samah, Harding, Shane, Chan, Norman, Bristow, Robert, Sanchez, Otto, Durocher, Daniel, Hakem, Razqallah
Publicado em 2010

RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks

Por Bohgaki, Miyuki, Bohgaki, Toshiyuki, El Ghamrasni, Samah, Srikumar, Tharan, Maire, Georges, Panier, Stephanie, Fradet-Turcotte, Amélie, Stewart, Grant S., Raught, Brian, Hakem, Anne, Hakem, Razqallah
Publicado em 2013

Inactivation of Chk2 and Mus81 Leads to Impaired Lymphocytes Development, Reduced Genomic Instability, and Suppression of Cancer

Por El Ghamrasni, Samah, Pamidi, Ashwin, Halaby, Marie Jo, Bohgaki, Miyuki, Cardoso, Renato, Li, Li, Venkatesan, Shriram, Sethu, Swaminathan, Hirao, Atsushi, Mak, Tak W., Hande, Manoor Prakash, Hakem, Anne, Hakem, Razqallah
Publicado em 2011

RNF168 and USP10 regulate topoisomerase IIα function via opposing effects on its ubiquitylation

Por Guturi, Kiran Kumar Naidu, Bohgaki, Miyuki, Bohgaki, Toshiyuki, Srikumar, Tharan, Ng, Deborah, Kumareswaran, Ramya, El Ghamrasni, Samah, Jeon, Justin, Patel, Parasvi, Eldin, Mohamed Saad, Bristow, Rob, Cheung, Peter, Stewart, Grant S., Raught, Brian, Hakem, Anne, Hakem, Razqallah
Publicado no Nat Commun (2016)

Systemic ceramide accumulation leads to severe and varied pathological consequences

Por Alayoubi, Abdulfatah M, Wang, James C M, Au, Bryan C Y, Carpentier, Stéphane, Garcia, Virginie, Dworski, Shaalee, El-Ghamrasni, Samah, Kirouac, Kevin N, Exertier, Mathilde J, Xiong, Zi Jian, Privé, Gilbert G, Simonaro, Calogera M, Casas, Josefina, Fabrias, Gemma, Schuchman, Edward H, Turner, Patricia V, Hakem, Razqallah, Levade, Thierry, Medin, Jeffrey A
Publicado em 2013