RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks

Defective signaling or repair of DNA double-strand breaks has been associated with developmental defects and human diseases. The E3 ligase RING finger 168 (RNF168), mutated in the human radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome, was shown to ubiquity...

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Библиографические подробности
Главные авторы: Bohgaki, Miyuki, Bohgaki, Toshiyuki, El Ghamrasni, Samah, Srikumar, Tharan, Maire, Georges, Panier, Stephanie, Fradet-Turcotte, Amélie, Stewart, Grant S., Raught, Brian, Hakem, Anne, Hakem, Razqallah
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2013
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876264/
https://ncbi.nlm.nih.gov/pubmed/24324146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320302111
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