RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks

Defective signaling or repair of DNA double-strand breaks has been associated with developmental defects and human diseases. The E3 ligase RING finger 168 (RNF168), mutated in the human radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties syndrome, was shown to ubiquity...

詳細記述

保存先:
書誌詳細
主要な著者: Bohgaki, Miyuki, Bohgaki, Toshiyuki, El Ghamrasni, Samah, Srikumar, Tharan, Maire, Georges, Panier, Stephanie, Fradet-Turcotte, Amélie, Stewart, Grant S., Raught, Brian, Hakem, Anne, Hakem, Razqallah
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2013
主題:
Biological Sciences
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876264/
https://ncbi.nlm.nih.gov/pubmed/24324146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320302111
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