MIP-1α/CCL3-mediated maintenance of leukemia-initiating cells in the initiation process of chronic myeloid leukemia

Por Baba, Tomohisa, Naka, Kazuhito, Morishita, Soji, Komatsu, Norio, Hirao, Atsushi, Mukaida, Naofumi
Publicado em 2013

S6 Kinase- and β-TrCP2-Dependent Degradation of p19(Arf) Is Required for Cell Proliferation

Por Nakagawa, Tadashi, Araki, Takaaki, Nakagawa, Makiko, Hirao, Atsushi, Unno, Michiaki, Nakayama, Keiko
Publicado no Mol Cell Biol (2015)

Chk2 is dispensable for p53-mediated G(1) arrest but is required for a latent p53-mediated apoptotic response

Por Jack, Melissa T., Woo, Richard A., Hirao, Atsushi, Cheung, Alison, Mak, Tak W., Lee, Patrick W. K.
Publicado em 2002

Activated macrophages promote Wnt signalling through tumour necrosis factor-α in gastric tumour cells

Por Oguma, Keisuke, Oshima, Hiroko, Aoki, Masahiro, Uchio, Ryusei, Naka, Kazuhito, Nakamura, Satoshi, Hirao, Atsushi, Saya, Hideyuki, Taketo, Makoto Mark, Oshima, Masanobu
Publicado em 2008

mTORC1 is essential for leukemia propagation but not stem cell self-renewal

Por Hoshii, Takayuki, Tadokoro, Yuko, Naka, Kazuhito, Ooshio, Takako, Muraguchi, Teruyuki, Sugiyama, Naoyuki, Soga, Tomoyoshi, Araki, Kimi, Yamamura, Ken-ichi, Hirao, Atsushi
Publicado em 2012

Cross-talk between Chk1 and Chk2 in double-mutant thymocytes

Por Zaugg, Kathrin, Su, Yu-Wen, Reilly, Patrick T., Moolani, Yasmin, Cheung, Carol C., Hakem, Razquallah, Hirao, Atsushi, Liu, Quinghua, Elledge, Stephen J., Mak, Tak W.
Publicado em 2007

Invasion Precedes Tumor Mass Formation in a Malignant Brain Tumor Model of Genetically Modified Neural Stem Cells

Por Sampetrean, Oltea, Saga, Isako, Nakanishi, Masaya, Sugihara, Eiji, Fukaya, Raita, Onishi, Nobuyuki, Osuka, Satoru, Akahata, Masaki, Kai, Kazuharu, Sugimoto, Hachiro, Hirao, Atsushi, Saya, Hideyuki
Publicado em 2011

Differences of AMPA and kainate receptor interactomes identify a novel AMPA receptor auxiliary subunit, GSG1L

Por Shanks, Natalie F., Savas, Jeffrey N., Maruo, Tomohiko, Cais, Ondrej, Hirao, Atsushi, Oe, Souichi, Ghosh, Anirvan, Noda, Yasuko, Greger, Ingo H., Yates, John R., Nakagawa, Terunaga
Publicado em 2012

Therapeutic Strategy for Targeting Aggressive Malignant Gliomas by Disrupting Their Energy Balance

Por Hegazy, Ahmed M., Yamada, Daisuke, Kobayashi, Masahiko, Kohno, Susumu, Ueno, Masaya, Ali, Mohamed A. E., Ohta, Kumiko, Tadokoro, Yuko, Ino, Yasushi, Todo, Tomoki, Soga, Tomoyoshi, Takahashi, Chiaki, Hirao, Atsushi
Publicado no J Biol Chem (2016)

Chk2 regulates irradiation-induced, p53-mediated apoptosis in Drosophila

Por Peters, Malte, DeLuca, Carmela, Hirao, Atsushi, Stambolic, Vuk, Potter, Julia, Zhou, Lily, Liepa, Jennifer, Snow, Bryan, Arya, Sudha, Wong, Jorge, Bouchard, Denis, Binari, Richard, Manoukian, Armen S., Mak, Tak W.
Publicado em 2002

Inactivation of Chk2 and Mus81 Leads to Impaired Lymphocytes Development, Reduced Genomic Instability, and Suppression of Cancer

Por El Ghamrasni, Samah, Pamidi, Ashwin, Halaby, Marie Jo, Bohgaki, Miyuki, Cardoso, Renato, Li, Li, Venkatesan, Shriram, Sethu, Swaminathan, Hirao, Atsushi, Mak, Tak W., Hande, Manoor Prakash, Hakem, Anne, Hakem, Razqallah
Publicado em 2011

Loss of mTOR complex 1 induces developmental blockage in early T-lymphopoiesis and eradicates T-cell acute lymphoblastic leukemia cells

Por Hoshii, Takayuki, Kasada, Atsuo, Hatakeyama, Tomoki, Ohtani, Masashi, Tadokoro, Yuko, Naka, Kazuhito, Ikenoue, Tsuneo, Ikawa, Tomokatsu, Kawamoto, Hiroshi, Fehling, Hans Joerg, Araki, Kimi, Yamamura, Ken-ichi, Matsuda, Satoshi, Hirao, Atsushi
Publicado em 2014

Real-time in vivo imaging of p16(Ink4a) reveals cross talk with p53

Por Yamakoshi, Kimi, Takahashi, Akiko, Hirota, Fumiko, Nakayama, Rika, Ishimaru, Naozumi, Kubo, Yoshiaki, Mann, David J., Ohmura, Masako, Hirao, Atsushi, Saya, Hideyuki, Arase, Seiji, Hayashi, Yoshio, Nakao, Kazuki, Matsumoto, Mitsuru, Ohtani, Naoko, Hara, Eiji
Publicado em 2009

Collaboration of Brca1 and Chk2 in tumorigenesis

Por McPherson, John Peter, Lemmers, Bénédicte, Hirao, Atsushi, Hakem, Anne, Abraham, Jacinth, Migon, Eva, Matysiak-Zablocki, Elzbieta, Tamblyn, Laura, Sanchez-Sweatman, Otto, Khokha, Rama, Squire, Jeremy, Hande, M. Prakash, Mak, Tak W., Hakem, Razqallah
Publicado em 2004

14-3-3σ regulates B-cell homeostasis through stabilization of FOXO1

Por Su, Yu-Wen, Hao, Zhenyue, Hirao, Atsushi, Yamamoto, Kazuo, Lin, Wen-Jye, Young, Ashley, Duncan, Gordon S., Yoshida, Hiroki, Wakeham, Andrew, Lang, Philipp A., Murakami, Kiichi, Hermeking, Heiko, Vogelstein, Bert, Ohashi, Pamela, Mak, Tak W.
Publicado em 2011

Visualizing the dynamics of p21(Waf1/Cip1) cyclin-dependent kinase inhibitor expression in living animals

Por Ohtani, Naoko, Imamura, Yuko, Yamakoshi, Kimi, Hirota, Fumiko, Nakayama, Rika, Kubo, Yoshiaki, Ishimaru, Naozumi, Takahashi, Akiko, Hirao, Atsushi, Shimizu, Takatsune, Mann, David J., Saya, Hideyuki, Hayashi, Yoshio, Arase, Seiji, Matsumoto, Mitsuru, Kazuki, Nakao, Hara, Eiji
Publicado em 2007

Identification of tumor-initiating cells in a highly aggressive brain tumor using promoter activity of nucleostemin

Por Tamase, Akira, Muraguchi, Teruyuki, Naka, Kazuhito, Tanaka, Shingo, Kinoshita, Masashi, Hoshii, Takayuki, Ohmura, Masako, Shugo, Haruhiko, Ooshio, Takako, Nakada, Mitsutoshi, Sawamoto, Kazunobu, Onodera, Masafumi, Matsumoto, Kunio, Oshima, Masanobu, Asano, Masahide, Saya, Hideyuki, Okano, Hideyuki, Suda, Toshio, Hamada, Jun-ichiro, Hirao, Atsushi
Publicado em 2009

Chk2 Is a Tumor Suppressor That Regulates Apoptosis in both an Ataxia Telangiectasia Mutated (ATM)-Dependent and an ATM-Independent Manner

Por Hirao, Atsushi, Cheung, Alison, Duncan, Gordon, Girard, Pierre-Marie, Elia, Andrew J., Wakeham, Andrew, Okada, Hitoshi, Sarkissian, Talin, Wong, Jorge A., Sakai, Takashi, de Stanchina, Elisa, Bristow, Robert G., Suda, Toshio, Lowe, Scott W., Jeggo, Penny A., Elledge, Stephen J., Mak, Tak W.
Publicado em 2002

Novel oral transforming growth factor‐β signaling inhibitor EW‐7197 eradicates CML‐initiating cells

Por Naka, Kazuhito, Ishihara, Kaori, Jomen, Yoshie, Jin, Cheng Hua, Kim, Dong‐Hyun, Gu, Yoon‐Kang, Jeong, Eun‐Sook, Li, Shaoguang, Krause, Daniela S., Kim, Dong‐Wook, Bae, Eunjin, Takihara, Yoshihiro, Hirao, Atsushi, Oshima, Hiroko, Oshima, Masanobu, Ooshima, Akira, Sheen, Yhun Yhong, Kim, Seong‐Jin, Kim, Dae‐Kee
Publicado no Cancer Sci (2016)

Displays of paternal mouse pup retrieval following communicative interaction with maternal mates

Por Liu, Hong-Xiang, Lopatina, Olga, Higashida, Chiharu, Fujimoto, Hiroko, Akther, Shirin, Inzhutova, Alena, Liang, Mingkun, Zhong, Jing, Tsuji, Takahiro, Yoshihara, Toru, Sumi, Kohei, Ishiyama, Mizuho, Ma, Wen-Jie, Ozaki, Mitsunori, Yagitani, Satoshi, Yokoyama, Shigeru, Mukaida, Naofumi, Sakurai, Takeshi, Hori, Osamu, Yoshioka, Katsuji, Hirao, Atsushi, Kato, Yukio, Ishihara, Katsuhiko, Kato, Ichiro, Okamoto, Hiroshi, Cherepanov, Stanislav M., Salmina, Alla B., Hirai, Hirokazu, Asano, Masahide, Brown, David A., Nagano, Isamu, Higashida, Haruhiro
Publicado em 2013