Activated macrophages promote Wnt signalling through tumour necrosis factor-α in gastric tumour cells

The activation of Wnt/β-catenin signalling has an important function in gastrointestinal tumorigenesis. It has been suggested that the promotion of Wnt/β-catenin activity beyond the threshold is important for carcinogenesis. We herein investigated the role of macrophages in the promotion of Wnt/β-ca...

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Main Authors: Oguma, Keisuke, Oshima, Hiroko, Aoki, Masahiro, Uchio, Ryusei, Naka, Kazuhito, Nakamura, Satoshi, Hirao, Atsushi, Saya, Hideyuki, Taketo, Makoto Mark, Oshima, Masanobu
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2413189/
https://ncbi.nlm.nih.gov/pubmed/18511911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.105
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