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Hyperplastic gastric tumors induced by activated macrophages in COX-2/mPGES-1 transgenic mice

Cyclooxygenase-2 (COX-2), the rate-limiting enzyme for prostanoid biosynthesis, plays a key role in gastrointestinal carcinogenesis. Among various prostanoids, prostaglandin E(2) (PGE(2)) appears to be most responsible for cancer development. To investigate the role of PGE(2) in gastric tumorigenesi...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Oshima, Hiroko, Oshima, Masanobu, Inaba, Kayo, Taketo, Makoto M
Format: Artigo
Langue:Inglês
Publié: 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC391075/
https://ncbi.nlm.nih.gov/pubmed/15014433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600170
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