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Hyperplastic gastric tumors induced by activated macrophages in COX-2/mPGES-1 transgenic mice
Cyclooxygenase-2 (COX-2), the rate-limiting enzyme for prostanoid biosynthesis, plays a key role in gastrointestinal carcinogenesis. Among various prostanoids, prostaglandin E(2) (PGE(2)) appears to be most responsible for cancer development. To investigate the role of PGE(2) in gastric tumorigenesi...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC391075/ https://ncbi.nlm.nih.gov/pubmed/15014433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600170 |
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