Simultaneous expression of COX-2 and mPGES-1 in mouse gastrointestinal hamartomas

Cyclo-oxygenase (COX)-2 is induced in various types of cancer tissues. Here, we demonstrate stromal expression of both COX-2 and microsomal prostaglandin E(2) synthase (mPGES)-1 in gastrointestinal hamartomas developed in Lkb1(+/−), Smad4(+/−) and Cdx2(+/−)mice. These results suggest that PGE(2) pro...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Takeda, H, Miyoshi, H, Tamai, Y, Oshima, M, Taketo, M M
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2004
Sujets:
Experimental Therapeutics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409590/
https://ncbi.nlm.nih.gov/pubmed/14760387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601584
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