Poly(I:C) increases the expression of mPGES-1 and COX-2 in rat primary microglia

BACKGROUND: Microglia recognize pathogen-associated molecular patterns such as double-stranded RNA (dsRNA) present in some viruses. Polyinosinic-polycytidylic acid [poly(I:C)] is a synthetic analog of dsRNA that activates different molecules, such as retinoic acid-inducible gene I, melanoma differen...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: de Oliveira, Antonio Carlos Pinheiro, Yousif, Nizar M., Bhatia, Harsharan Singh, Hermanek, Julia, Huell, Michael, Fiebich, Bernd L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717620/
https://ncbi.nlm.nih.gov/pubmed/26780827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0473-7
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