Mammary Gland Reprogramming: Metalloproteinases Couple Form with Function

Por Khokha, Rama, Werb, Zena
Publicado em 2011

The mammary stem cell conundrum: is it unipotent or multipotent?

Por Joshi, Purna A, Khokha, Rama
Publicado em 2012

Tumor suppression by stromal TIMPs

Por Shimoda, Masayuki, Jackson, Hartland W., Khokha, Rama
Publicado no Mol Cell Oncol (2016)

Inflammation and breast cancer. Metalloproteinases as common effectors of inflammation and extracellular matrix breakdown in breast cancer

Por Hojilla, Carlo V, Wood, Geoffrey A, Khokha, Rama
Publicado em 2008

TIMP3 Regulates Mammary Epithelial Apoptosis with Immune Cell Recruitment Through Differential TNF Dependence

Por Hojilla, Carlo V., Jackson, Hartland W., Khokha, Rama
Publicado em 2011

Fully Interlocking: A Story of Teamwork amongst Breast Epithelial Cells

Por Alexander, Caroline M., Joshi, Purna A., Khokha, Rama
Publicado em 2014

Lack of Tissue Inhibitor of Metalloproteinases-3 Results in an Enhanced Inflammatory Response in Antigen-Induced Arthritis

Por Mahmoodi, Mandana, Sahebjam, Solmaz, Smookler, David, Khokha, Rama, Mort, John S.
Publicado em 2005

Insulin-like Growth Factor II Signaling in Neoplastic Proliferation Is Blocked by Transgenic Expression of the Metalloproteinase Inhibitor Timp-1

Por Martin, David C., Fowlkes, John L., Babic, Bojana, Khokha, Rama
Publicado em 1999

Calcium pentosan polysulfate is a multifaceted exosite inhibitor of aggrecanases

Por Troeberg, Linda, Fushimi, Kazunari, Khokha, Rama, Emonard, Hervé, Ghosh, Peter, Nagase, Hideaki
Publicado em 2008

Binding to EGF receptor of a laminin-5 EGF-like fragment liberated during MMP-dependent mammary gland involution

Por Schenk, Susann, Hintermann, Edith, Bilban, Martin, Koshikawa, Naohiko, Hojilla, Carlo, Khokha, Rama, Quaranta, Vito
Publicado em 2003

Timp3 Deficient Mice Show Resistance to Developing Breast Cancer

Por Jackson, Hartland W., Hojilla, Carlo V., Weiss, Ashley, Sanchez, Otto H., Wood, Geoffrey A., Khokha, Rama
Publicado no PLoS One (2015)

RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis

Por Hakem, Anne, Sanchez-Sweatman, Otto, You-Ten, Annick, Duncan, Gordon, Wakeham, Andrew, Khokha, Rama, Mak, Tak W.
Publicado em 2005

Simultaneous Transforming Growth Factor β-Tumor Necrosis Factor Activation and Cross-talk Cause Aberrant Remodeling Response and Myocardial Fibrosis in Timp3-deficient Heart

Por Kassiri, Zamaneh, Defamie, Virginie, Hariri, Mehrdad, Oudit, Gavin Y., Anthwal, Shalini, Dawood, Fayez, Liu, Peter, Khokha, Rama
Publicado em 2009

Tissue Inhibitor of Metalloproteinases 3 Regulates Resolution of Inflammation following Acute Lung Injury

Por Gill, Sean E., Huizar, Isham, Bench, Eli M., Sussman, Samuel W., Wang, Ying, Khokha, Rama, Parks, William C.
Publicado em 2010

Ectodomain shedding of EGFR ligands and TNFR1 dictates hepatocyte apoptosis during fulminant hepatitis in mice

Por Murthy, Aditya, Defamie, Virginie, Smookler, David S., Di Grappa, Marco A., Horiuchi, Keisuke, Federici, Massimo, Sibilia, Maria, Blobel, Carl P., Khokha, Rama
Publicado em 2010

Increased Neovascularization in Mice Lacking Tissue Inhibitor of Metalloproteinases-3

Por Ebrahem, Quteba, Qi, Jian Hua, Sugimoto, Masahiko, Ali, Mariya, Sears, Jonathan E., Cutler, Alecia, Khokha, Rama, Vasanji, Amit, Anand-Apte, Bela
Publicado em 2011

Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases-3 (TIMP-3)

Por Leco, Kevin J., Waterhouse, Paul, Sanchez, Otto H., Gowing, Katrina L.M., Poole, A. Robin, Wakeham, Andrew, Mak, Tak W., Khokha, Rama
Publicado em 2001

Accelerated apoptosis in the Timp-3–deficient mammary gland

Por Fata, Jimmie E., Leco, Kevin J., Voura, Evelyn B., Yu, Hoi-Ying E., Waterhouse, Paul, Murphy, Gillian, Moorehead, Roger A., Khokha, Rama
Publicado em 2001

Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases-3 (TIMP-3)

Por Leco, Kevin J., Waterhouse, Paul, Sanchez, Otto H., Gowing, Katrina L.M., Poole, A. Robin, Wakeham, Andrew, Mak, Tak W., Khokha, Rama
Publicado em 2001

Proteolysis during Tumor Cell Extravasation In Vitro: Metalloproteinase Involvement across Tumor Cell Types

Por Voura, Evelyn B., English, Jane L., Yu, Hoi-Ying E., Ho, Andrew T., Subarsky, Patrick, Hill, Richard P., Hojilla, Carlo V., Khokha, Rama
Publicado em 2013