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Proteolysis during Tumor Cell Extravasation In Vitro: Metalloproteinase Involvement across Tumor Cell Types

To test if proteolysis is involved in tumor cell extravasation, we developed an in vitro model where tumor cells cross an endothelial monolayer cultured on a basement membrane. Using this model we classified the ability of the cells to transmigrate through the endothelial cell barrier onto the under...

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Detalhes bibliográficos
Main Authors: Voura, Evelyn B., English, Jane L., Yu, Hoi-Ying E., Ho, Andrew T., Subarsky, Patrick, Hill, Richard P., Hojilla, Carlo V., Khokha, Rama
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3806793/
https://ncbi.nlm.nih.gov/pubmed/24194929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078413
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