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Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases-3 (TIMP-3)

Tissue inhibitors of metalloproteinases regulate ECM degradation by matrix metalloproteinases (MMPs). We have developed a mouse line deficient for tissue inhibitor of metalloproteinases-3 (TIMP-3), the only TIMP known to reside within the ECM. Homozygous Timp-3–null animals develop spontaneous air s...

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Bibliographische Detailangaben
Hauptverfasser: Leco, Kevin J., Waterhouse, Paul, Sanchez, Otto H., Gowing, Katrina L.M., Poole, A. Robin, Wakeham, Andrew, Mak, Tak W., Khokha, Rama
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC200926/
https://ncbi.nlm.nih.gov/pubmed/11560951
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