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RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis
The Rho proteins are Ras-related guanosine triphosphatases (GTPases) that function in cytoskeletal reorganization, cell migration, and stress fiber and focal adhesion formation. Overexpression of RhoC enhances the ability of melanoma cells to exit the blood and colonize the lungs. However, in vivo c...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1199568/ https://ncbi.nlm.nih.gov/pubmed/16107613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1310805 |
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