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RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis
The Rho proteins are Ras-related guanosine triphosphatases (GTPases) that function in cytoskeletal reorganization, cell migration, and stress fiber and focal adhesion formation. Overexpression of RhoC enhances the ability of melanoma cells to exit the blood and colonize the lungs. However, in vivo c...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Cold Spring Harbor Laboratory Press
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1199568/ https://ncbi.nlm.nih.gov/pubmed/16107613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1310805 |
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