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Atorvastatin inhibits RhoC function and limits head and neck cancer metastasis

OBJECTIVE: RhoC oncogene is a well characterized marker of metastasis in a majority of invasive cancers, including HNSCC. Elevated RhoC expression has been found to be associated with distant metastasis. Statins are a class of drugs that are used to reduce cholesterol levels by inhibiting HMG-CoA re...

詳細記述

保存先:
書誌詳細
出版年:Oral Oncol
主要な著者: Islam, Mozaffarul, Sharma, Smita, Kumar, Bhavna, Teknos, Theodoros N.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299638/
https://ncbi.nlm.nih.gov/pubmed/23648017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.oraloncology.2013.04.003
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