RhoC Regulates Cancer Stem Cells in Head and Neck Squamous Cell Carcinoma by Overexpressing IL-6 and Phosphorylation of STAT3

In this study we investigated the correlation between RhoC expression and cancer stem cells (CSCs) formation in head and neck squamous cell carcinoma (HNSCC). The inhibition of RhoC function was achieved using shRNA. The expression of stem cell surface markers, ALDH and CD44 were significantly low i...

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Bibliografiska uppgifter
Huvudupphovsmän: Islam, Mozaffarul, Sharma, Smita, Teknos, Theodoros N.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922885/
https://ncbi.nlm.nih.gov/pubmed/24533098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088527
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