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Atorvastatin prevents RhoC isoprenylation, invasion, and metastasis in human melanoma cells

Melanoma is a deadly cancer due to its propensity to metastasize. Pharmacological inhibition of cell motility may benefit patients with cutaneous melanoma by preventing metastasis to internal organs. The Rho GTPases are signaling molecules that drive metastasis by controlling cell motility. We found...

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Huvudupphovsmän: Collisson, Eric A., Kleer, Celina, Wu, Mei, De, Abhijit, Gambhir, Sanjiv S., Merajver, Sofia D., Kolodney, Michael S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2003
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4161126/
https://ncbi.nlm.nih.gov/pubmed/14578459
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