Therapeutic Strategy for Targeting Aggressive Malignant Gliomas by Disrupting Their Energy Balance

Although abnormal metabolic regulation is a critical determinant of cancer cell behavior, it is still unclear how an altered balance between ATP production and consumption contributes to malignancy. Here we show that disruption of this energy balance efficiently suppresses aggressive malignant gliom...

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Foilsithe in:J Biol Chem
Main Authors: Hegazy, Ahmed M., Yamada, Daisuke, Kobayashi, Masahiko, Kohno, Susumu, Ueno, Masaya, Ali, Mohamed A. E., Ohta, Kumiko, Tadokoro, Yuko, Ino, Yasushi, Todo, Tomoki, Soga, Tomoyoshi, Takahashi, Chiaki, Hirao, Atsushi
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2016
Ábhair:
Metabolism
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076821/
https://ncbi.nlm.nih.gov/pubmed/27519418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.734756
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