The role of the SWI/SNF chromatin remodeling complex in maintaining the stemness of glioma initiating cells

Glioma initiating cells (GICs) are thought to contribute to therapeutic resistance and tumor recurrence in glioblastoma, a lethal primary brain tumor in adults. Although the stem-like properties of GICs, such as self-renewal and tumorigenicity, are epigenetically regulated, the role of a major chrom...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Hiramatsu, Hiroaki, Kobayashi, Kazuyoshi, Kobayashi, Kyousuke, Haraguchi, Takeshi, Ino, Yasushi, Todo, Tomoki, Iba, Hideo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429847/
https://ncbi.nlm.nih.gov/pubmed/28420882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00982-3
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