MiR-199a Inhibits Secondary Envelopment of Herpes Simplex Virus-1 Through the Downregulation of Cdc42-specific GTPase Activating Protein Localized in Golgi Apparatus

Because several studies have shown that exogenous miR-199a has antiviral effects against various viruses, including herpesviruses, we examined how miR-199a exerts its antiviral effects using epithelial tumour cell lines infected with herpes simplex virus-1 (HSV-1). We found that both miR-199a-5p and...

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Publicat a:Sci Rep
Autors principals: Kobayashi, Kyousuke, Suemasa, Fumiko, Sagara, Hiroshi, Nakamura, Shinya, Ino, Yasushi, Kobayashi, Kazuyoshi, Hiramatsu, Hiroaki, Haraguchi, Takeshi, Kurokawa, Kazuo, Todo, Tomoki, Nakano, Akihiko, Iba, Hideo
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5532371/
https://ncbi.nlm.nih.gov/pubmed/28751779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06754-3
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