Loading...

SWI/SNF Chromatin Remodeling Complexes and Cancer

The identification of mutations and deletions in the SMARCB1 locus in chromosome band 22q11.2 in pediatric rhabdoid tumors provided the first evidence for the involvement of the SWI/SNF chromatin remodeling complex in cancer. Over the last 15 years, alterations in more than 20 members of the complex...

Full description

Saved in:
Bibliographic Details
Published in:Am J Med Genet C Semin Med Genet
Main Authors: Biegel, Jaclyn A, Busse, Tracy M., Weissman, Bernard E.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516040/
https://ncbi.nlm.nih.gov/pubmed/25169151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.c.31410
Tags: Add Tag
No Tags, Be the first to tag this record!