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Remodeling the cancer epigenome: mutations in the SWI/SNF complex offer new therapeutic opportunities
INTRODUCTION: Cancer genome sequencing studies have discovered mutations in members of the SWItch/Sucrose Non-Fermentable (SWI/SNF) chromatin-remodeling complex in nearly 25% of human cancers. The SWI/SNF complex, first discovered in S. cerevisiae, shows strong conservation from yeast to Drosophila...
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| Publicado en: | Expert Rev Anticancer Ther |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6533634/ https://ncbi.nlm.nih.gov/pubmed/30986130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14737140.2019.1605905 |
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