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Exploiting vulnerabilities of SWI/SNF chromatin remodelling complexes for cancer therapy
Multi-subunit ATPase-dependent chromatin remodelling complexes SWI/SNF (switch/sucrose non-fermentable) are fundamental epigenetic regulators of gene transcription. Functional genomic studies revealed a remarkable mutation prevalence of SWI/SNF-encoding genes in 20–25% of all human cancers, frequent...
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| Publicado no: | Oncogene |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8154588/ https://ncbi.nlm.nih.gov/pubmed/33941852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-021-01781-x |
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