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Vulnerabilities of mutant SWI/SNF complexes in cancer
Cancer genome sequencing efforts have revealed the novel theme that chromatin modifiers are frequently mutated across a wide spectrum of cancers. Mutations in genes encoding subunits of SWI/SNF (BAF) chromatin remodeling complexes are particularly prevalent, occurring in 20% of all human cancers. As...
में बचाया:
| मुख्य लेखकों: | , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2014
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4159614/ https://ncbi.nlm.nih.gov/pubmed/25203320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2014.07.018 |
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