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Deletion of MCP-1 Impedes Pathogenesis of Acid Ceramidase Deficiency

Farber Disease (FD) is an ultra-rare Lysosomal Storage Disorder caused by deficient acid ceramidase (ACDase) activity. Patients with ACDase deficiency manifest a spectrum of symptoms including formation of nodules, painful joints, and a hoarse voice. Classic FD patients will develop histiocytes in o...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yu, Fabian P. S., Dworski, Shaalee, Medin, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789088/
https://ncbi.nlm.nih.gov/pubmed/29379059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20052-6
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