Proteotyping of knockout mouse strains reveals sex- and strain-specific signatures in blood plasma

por Mohammed, Yassene, Michaud, Sarah A., Pětrošová, Helena, Yang, Juncong, Ganguly, Milan, Schibli, David, Flenniken, Ann M., Nutter, Lauryl M. J., Adissu, Hibret A., Lloyd, K. C. Kent, McKerlie, Colin, Borchers, Christoph H.
Publicado en NPJ Syst Biol Appl (2021)

Cytopenia induction by 5-fluorouracil identifies thrombopoietic mutants in sensitized ENU mutagenesis screens

por Anderson, Nicole M., Berberovic, Zorana, Berndl, Elizabeth, Bailey, Monica L., Flenniken, Ann M., Osborne, Lucy R., Adamson, S. Lee, Rossant, Janet, Wang, Chen, Minden, Mark D., McNagny, Kelly M., Paulson, Robert F., Barber, Dwayne L., Stanford, William L.
Publicado 2011

Genome-wide screening of mouse knockouts reveals novel genes required for normal integumentary and oculocutaneous structure and function

por Moore, Bret A., Flenniken, Ann M., Clary, Dave, Moshiri, Ata S., Nutter, Lauryl M. J., Berberovic, Zorana, Owen, Celeste, Newbigging, Susan, Adissu, Hibret, Eskandarian, Mohammad, McKerlie, Colin, Thomasy, Sara M., Lloyd, K. C. Kent, Murphy, Christopher J., Moshiri, Ala
Publicado en Sci Rep (2019)

Enu Mutagenesis Identifies a Novel Platelet Phenotype in a Loss-Of-Function Jak2 Allele

por Anderson, Nicole M., Javadi, Mojib, Berndl, Elizabeth, Berberovic, Zorana, Bailey, Monica L., Huang, Kai, Flenniken, Ann M., Osborne, Lucy R., Adamson, S. Lee, Rossant, Janet, Carter-Su, Christin, Wang, Chen, McNagny, Kelly M., Paulson, Robert F., Minden, Mark D., Stanford, William L., Barber, Dwayne L.
Publicado 2013

The occurrence of tarsal injuries in male mice of C57BL/6N substrains in multiple international mouse facilities

por Herbert, Eleanor, Stewart, Michelle, Hutchison, Marie, Flenniken, Ann M., Qu, Dawei, Nutter, Lauryl M. J., McKerlie, Colin, Hobson, Liane, Kick, Brenda, Lyons, Bonnie, Wiegand, Jean-Paul, Doty, Rosalinda, Aguilar-Pimentel, Juan Antonio, Hrabe de Angelis, Martin, Dickinson, Mary, Seavitt, John, White, Jacqueline K., Scudamore, Cheryl L., Wells, Sara
Publicado en PLoS One (2020)

A Comprehensive Plasma Metabolomics Dataset for a Cohort of Mouse Knockouts within the International Mouse Phenotyping Consortium

por Barupal, Dinesh K., Zhang, Ying, Shen, Tong, Fan, Sili, Roberts, Bryan S., Fitzgerald, Patrick, Wancewicz, Benjamin, Valdiviez, Luis, Wohlgemuth, Gert, Byram, Gregory, Choy, Ying Yng, Haffner, Bennett, Showalter, Megan R., Vaniya, Arpana, Bloszies, Clayton S., Folz, Jacob S., Kind, Tobias, Flenniken, Ann M., McKerlie, Colin, Nutter, Lauryl M. J., Lloyd, Kent C., Fiehn, Oliver
Publicado en Metabolites (2019)

ENU-induced Mutation in the DNA-binding Domain of KLF3 Reveals Important Roles for KLF3 in Cardiovascular Development and Function in Mice

por Kelsey, Lois, Flenniken, Ann M., Qu, Dawei, Funnell, Alister P. W., Pearson, Richard, Zhou, Yu-Qing, Voronina, Irina, Berberovic, Zorana, Wood, Geoffrey, Newbigging, Susan, Weiss, Edward S., Wong, Michael, Quach, Ivan, Yeh, S. Y. Sandy, Deshwar, Ashish R., Scott, Ian C., McKerlie, Colin, Henkelman, Mark, Backx, Peter, Simpson, Jeremy, Osborne, Lucy, Rossant, Janet, Crossley, Merlin, Bruneau, Benoit, Adamson, S. Lee
Publicado 2013

The International Mouse Phenotyping Consortium (IMPC): a functional catalogue of the mammalian genome that informs conservation

por Muñoz-Fuentes, Violeta, Cacheiro, Pilar, Meehan, Terrence F., Aguilar-Pimentel, Juan Antonio, Brown, Steve D. M., Flenniken, Ann M., Flicek, Paul, Galli, Antonella, Mashhadi, Hamed Haseli, Hrabě de Angelis, Martin, Kim, Jong Kyoung, Lloyd, K. C. Kent, McKerlie, Colin, Morgan, Hugh, Murray, Stephen A., Nutter, Lauryl M. J., Reilly, Patrick T., Seavitt, John R., Seong, Je Kyung, Simon, Michelle, Wardle-Jones, Hannah, Mallon, Ann-Marie, Smedley, Damian, Parkinson, Helen E.
Publicado en Conserv Genet (2018)

Cage-lid hanging behavior as a translationally relevant measure of pain in mice

por Zhang, Hantao, Lecker, Irene, Collymore, Chereen, Dokova, Anastassia, Pham, Maian Christine, Rosen, Sarah F., Crawhall-Duk, Hayley, Zain, Maham, Valencia, Megan, Filippini, Helena Fetter, Li, Jerry, D'Souza, Abigail J., Cho, Chulmin, Michailidis, Vassilia, Whissell, Paul D., Patel, Ingita, Steenland, Hendrik W., Virginia Lee, Wai-Jane, Moayedi, Massieh, Sterley, Toni-Lee, Bains, Jaideep S., Stratton, Jo Anne, Matyas, John R., Biernaskie, Jeff, Dubins, David, Vukobradovic, Igor, Bezginov, Alexandr, Flenniken, Ann M., Martin, Loren J., Mogil, Jeffrey S., Bonin, Robert P.
Publicado en Pain (2021)

Applying the ARRIVE Guidelines to an In Vivo Database

por Karp, Natasha A., Meehan, Terry F., Morgan, Hugh, Mason, Jeremy C., Blake, Andrew, Kurbatova, Natalja, Smedley, Damian, Jacobsen, Julius, Mott, Richard F., Iyer, Vivek, Matthews, Peter, Melvin, David G., Wells, Sara, Flenniken, Ann M., Masuya, Hiroshi, Wakana, Shigeharu, White, Jacqueline K., Lloyd, K. C. Kent, Reynolds, Corey L., Paylor, Richard, West, David B., Svenson, Karen L., Chesler, Elissa J., de Angelis, Martin Hrabě, Tocchini-Valentini, Glauco P., Sorg, Tania, Herault, Yann, Parkinson, Helen, Mallon, Ann-Marie, Brown, Steve D. M.
Publicado en PLoS Biol (2015)

High-throughput discovery of genetic determinants of circadian misalignment

por Zhang, Tao, Xie, Pancheng, Dong, Yingying, Liu, Zhiwei, Zhou, Fei, Pan, Dejing, Huang, Zhengyun, Zhai, Qiaocheng, Gu, Yue, Wu, Qingyu, Tanaka, Nobuhiko, Obata, Yuichi, Bradley, Allan, Lelliott, Christopher J., Nutter, Lauryl M. J., McKerlie, Colin, Flenniken, Ann M., Champy, Marie-France, Sorg, Tania, Herault, Yann, Angelis, Martin Hrabe De, Durner, Valerie Gailus, Mallon, Ann-Marie, Brown, Steve D. M., Meehan, Terry, Parkinson, Helen E., Smedley, Damian, Lloyd, K. C. Kent, Yan, Jun, Gao, Xiang, Seong, Je Kyung, Wang, Chi-Kuang Leo, Sedlacek, Radislav, Liu, Yi, Rozman, Jan, Yang, Ling, Xu, Ying
Publicado en PLoS Genet (2020)

Prevalence of sexual dimorphism in mammalian phenotypic traits

por Karp, Natasha A., Mason, Jeremy, Beaudet, Arthur L., Benjamini, Yoav, Bower, Lynette, Braun, Robert E., Brown, Steve D.M., Chesler, Elissa J., Dickinson, Mary E., Flenniken, Ann M., Fuchs, Helmut, Angelis, Martin Hrabe de, Gao, Xiang, Guo, Shiying, Greenaway, Simon, Heller, Ruth, Herault, Yann, Justice, Monica J., Kurbatova, Natalja, Lelliott, Christopher J., Lloyd, K.C. Kent, Mallon, Ann-Marie, Mank, Judith E., Masuya, Hiroshi, McKerlie, Colin, Meehan, Terrence F., Mott, Richard F., Murray, Stephen A., Parkinson, Helen, Ramirez-Solis, Ramiro, Santos, Luis, Seavitt, John R., Smedley, Damian, Sorg, Tania, Speak, Anneliese O., Steel, Karen P., Svenson, Karen L., Wakana, Shigeharu, West, David, Wells, Sara, Westerberg, Henrik, Yaacoby, Shay, White, Jacqueline K.
Publicado en Nat Commun (2017)

Human and mouse essentiality screens as a resource for disease gene discovery

por Cacheiro, Pilar, Muñoz-Fuentes, Violeta, Murray, Stephen A., Dickinson, Mary E., Bucan, Maja, Nutter, Lauryl M. J., Peterson, Kevin A., Haselimashhadi, Hamed, Flenniken, Ann M., Morgan, Hugh, Westerberg, Henrik, Konopka, Tomasz, Hsu, Chih-Wei, Christiansen, Audrey, Lanza, Denise G., Beaudet, Arthur L., Heaney, Jason D., Fuchs, Helmut, Gailus-Durner, Valerie, Sorg, Tania, Prochazka, Jan, Novosadova, Vendula, Lelliott, Christopher J., Wardle-Jones, Hannah, Wells, Sara, Teboul, Lydia, Cater, Heather, Stewart, Michelle, Hough, Tertius, Wurst, Wolfgang, Sedlacek, Radislav, Adams, David J., Seavitt, John R., Tocchini-Valentini, Glauco, Mammano, Fabio, Braun, Robert E., McKerlie, Colin, Herault, Yann, de Angelis, Martin Hrabě, Mallon, Ann-Marie, Lloyd, K. C.  Kent, Brown, Steve D. M., Parkinson, Helen, Meehan, Terrence F., Smedley, Damian
Publicado en Nat Commun (2020)

The Deep Genome Project

por Lloyd, K. C. Kent, Adams, David J., Baynam, Gareth, Beaudet, Arthur L., Bosch, Fatima, Boycott, Kym M., Braun, Robert E., Caulfield, Mark, Cohn, Ronald, Dickinson, Mary E., Dobbie, Michael S., Flenniken, Ann M., Flicek, Paul, Galande, Sanjeev, Gao, Xiang, Grobler, Anne, Heaney, Jason D., Herault, Yann, de Angelis, Martin Hrabě, Lupski, James R., Lyonnet, Stanislas, Mallon, Ann-Marie, Mammano, Fabio, MacRae, Calum A., McInnes, Roderick, McKerlie, Colin, Meehan, Terrence F., Murray, Stephen A., Nutter, Lauryl M. J., Obata, Yuichi, Parkinson, Helen, Pepper, Michael S., Sedlacek, Radislav, Seong, Je Kyung, Shiroishi, Toshihiko, Smedley, Damian, Tocchini-Valentini, Glauco, Valle, David, Wang, Chi-Kuang Leo, Wells, Sara, White, Jacqueline, Wurst, Wolfgang, Xu, Ying, Brown, Steve D. M.
Publicado en Genome Biol (2020)

A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction

por Bowl, Michael R., Simon, Michelle M., Ingham, Neil J., Greenaway, Simon, Santos, Luis, Cater, Heather, Taylor, Sarah, Mason, Jeremy, Kurbatova, Natalja, Pearson, Selina, Bower, Lynette R., Clary, Dave A., Meziane, Hamid, Reilly, Patrick, Minowa, Osamu, Kelsey, Lois, Tocchini-Valentini, Glauco P., Gao, Xiang, Bradley, Allan, Skarnes, William C., Moore, Mark, Beaudet, Arthur L., Justice, Monica J., Seavitt, John, Dickinson, Mary E., Wurst, Wolfgang, de Angelis, Martin Hrabe, Herault, Yann, Wakana, Shigeharu, Nutter, Lauryl M. J., Flenniken, Ann M., McKerlie, Colin, Murray, Stephen A., Svenson, Karen L., Braun, Robert E., West, David B., Lloyd, K. C. Kent, Adams, David J., White, Jacqui, Karp, Natasha, Flicek, Paul, Smedley, Damian, Meehan, Terrence F., Parkinson, Helen E., Teboul, Lydia M., Wells, Sara, Steel, Karen P., Mallon, Ann-Marie, Brown, Steve D. M.
Publicado en Nat Commun (2017)

Disease Model Discovery from 3,328 Gene Knockouts by The International Mouse Phenotyping Consortium

por Meehan, Terrence F., Conte, Nathalie, West, David B., Jacobsen, Julius O., Mason, Jeremy, Warren, Jonathan, Chen, Chao-Kung, Tudose, Ilinca, Relac, Mike, Matthews, Peter, Karp, Natasha, Santos, Luis, Fiegel, Tanja, Ring, Natalie, Westerberg, Henrik, Greenaway, Simon, Sneddon, Duncan, Morgan, Hugh, Codner, Gemma F, Stewart, Michelle E, Brown, James, Horner, Neil, Haendel, Melissa, Washington, Nicole, Mungall, Christopher J., Reynolds, Corey L, Gallegos, Juan, Gailus-Durner, Valerie, Sorg, Tania, Pavlovic, Guillaume, Bower, Lynette R, Moore, Mark, Morse, Iva, Gao, Xiang, Tocchini-Valentini, Glauco P, Obata, Yuichi, Cho, Soo Young, Seong, Je Kyung, Seavitt, John, Beaudet, Arthur L., Dickinson, Mary E., Herault, Yann, Wurst, Wolfgang, de Angelis, Martin Hrabe, Lloyd, K.C. Kent, Flenniken, Ann M, Nutter, Lauryl MJ, Newbigging, Susan, McKerlie, Colin, Justice, Monica J., Murray, Stephen A., Svenson, Karen L., Braun, Robert E., White, Jacqueline K., Bradley, Allan, Flicek, Paul, Wells, Sara, Skarnes, William C., Adams, David J., Parkinson, Helen, Mallon, Ann-Marie, Brown, Steve D.M., Smedley, Damian
Publicado en Nat Genet (2017)

Identification of genetic elements in metabolism by high-throughput mouse phenotyping

por Rozman, Jan, Rathkolb, Birgit, Oestereicher, Manuela A., Schütt, Christine, Ravindranath, Aakash Chavan, Leuchtenberger, Stefanie, Sharma, Sapna, Kistler, Martin, Willershäuser, Monja, Brommage, Robert, Meehan, Terrence F., Mason, Jeremy, Haselimashhadi, Hamed, Hough, Tertius, Mallon, Ann-Marie, Wells, Sara, Santos, Luis, Lelliott, Christopher J., White, Jacqueline K., Sorg, Tania, Champy, Marie-France, Bower, Lynette R., Reynolds, Corey L., Flenniken, Ann M., Murray, Stephen A., Nutter, Lauryl M. J., Svenson, Karen L., West, David, Tocchini-Valentini, Glauco P., Beaudet, Arthur L., Bosch, Fatima, Braun, Robert B., Dobbie, Michael S., Gao, Xiang, Herault, Yann, Moshiri, Ala, Moore, Bret A., Kent Lloyd, K. C., McKerlie, Colin, Masuya, Hiroshi, Tanaka, Nobuhiko, Flicek, Paul, Parkinson, Helen E., Sedlacek, Radislav, Seong, Je Kyung, Wang, Chi-Kuang Leo, Moore, Mark, Brown, Steve D., Tschöp, Matthias H., Wurst, Wolfgang, Klingenspor, Martin, Wolf, Eckhard, Beckers, Johannes, Machicao, Fausto, Peter, Andreas, Staiger, Harald, Häring, Hans-Ulrich, Grallert, Harald, Campillos, Monica, Maier, Holger, Fuchs, Helmut, Gailus-Durner, Valerie, Werner, Thomas, Hrabe de Angelis, Martin
Publicado en Nat Commun (2018)

Soft windowing application to improve analysis of high-throughput phenotyping data

por Haselimashhadi, Hamed, Mason, Jeremy C, Munoz-Fuentes, Violeta, López-Gómez, Federico, Babalola, Kolawole, Acar, Elif F, Kumar, Vivek, White, Jacqui, Flenniken, Ann M, King, Ruairidh, Straiton, Ewan, Seavitt, John Richard, Gaspero, Angelina, Garza, Arturo, Christianson, Audrey E, Hsu, Chih-Wei, Reynolds, Corey L, Lanza, Denise G, Lorenzo, Isabel, Green, Jennie R, Gallegos, Juan J, Bohat, Ritu, Samaco, Rodney C, Veeraragavan, Surabi, Kim, Jong Kyoung, Miller, Gregor, Fuchs, Helmult, Garrett, Lillian, Becker, Lore, Kang, Yeon Kyung, Clary, David, Cho, Soo Young, Tamura, Masaru, Tanaka, Nobuhiko, Soo, Kyung Dong, Bezginov, Alexandr, About, Ghina Bou, Champy, Marie-France, Vasseur, Laurent, Leblanc, Sophie, Meziane, Hamid, Selloum, Mohammed, Reilly, Patrick T, Spielmann, Nadine, Maier, Holger, Gailus-Durner, Valerie, Sorg, Tania, Hiroshi, Masuya, Yuichi, Obata, Heaney, Jason D, Dickinson, Mary E, Wolfgang, Wurst, Tocchini-Valentini, Glauco P, Lloyd, Kevin C Kent, McKerlie, Colin, Seong, Je Kyung, Yann, Herault, de Angelis, Martin Hrabé, Brown, Steve D M, Smedley, Damian, Flicek, Paul, Mallon, Ann-Marie, Parkinson, Helen, Meehan, Terrence F
Publicado en Bioinformatics (2020)

Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density

por Swan, Anna L., Schütt, Christine, Rozman, Jan, del Mar Muñiz Moreno, Maria, Brandmaier, Stefan, Simon, Michelle, Leuchtenberger, Stefanie, Griffiths, Mark, Brommage, Robert, Keskivali-Bond, Piia, Grallert, Harald, Werner, Thomas, Teperino, Raffaele, Becker, Lore, Miller, Gregor, Moshiri, Ala, Seavitt, John R., Cissell, Derek D., Meehan, Terrence F., Acar, Elif F., Lelliott, Christopher J., Flenniken, Ann M., Champy, Marie-France, Sorg, Tania, Ayadi, Abdel, Braun, Robert E., Cater, Heather, Dickinson, Mary E., Flicek, Paul, Gallegos, Juan, Ghirardello, Elena J., Heaney, Jason D., Jacquot, Sylvie, Lally, Connor, Logan, John G., Teboul, Lydia, Mason, Jeremy, Spielmann, Nadine, McKerlie, Colin, Murray, Stephen A., Nutter, Lauryl M. J., Odfalk, Kristian F., Parkinson, Helen, Prochazka, Jan, Reynolds, Corey L., Selloum, Mohammed, Spoutil, Frantisek, Svenson, Karen L., Vales, Taylor S., Wells, Sara E., White, Jacqueline K., Sedlacek, Radislav, Wurst, Wolfgang, Lloyd, K. C. Kent, Croucher, Peter I., Fuchs, Helmut, Williams, Graham R., Bassett, J. H. Duncan, Gailus-Durner, Valerie, Herault, Yann, Mallon, Ann-Marie, Brown, Steve D. M., Mayer-Kuckuk, Philipp, Hrabe de Angelis, Martin
Publicado en PLoS Genet (2020)

Identification of genes required for eye development by high-throughput screening of mouse knockouts

por Moore, Bret A., Leonard, Brian C., Sebbag, Lionel, Edwards, Sydney G., Cooper, Ann, Imai, Denise M., Straiton, Ewan, Santos, Luis, Reilly, Christopher, Griffey, Stephen M., Bower, Lynette, Clary, David, Mason, Jeremy, Roux, Michel J., Meziane, Hamid, Herault, Yann, McKerlie, Colin, Flenniken, Ann M., Nutter, Lauryl M. J., Berberovic, Zorana, Owen, Celeste, Newbigging, Susan, Adissu, Hibret, Eskandarian, Mohammed, Hsu, Chih-Wei, Kalaga, Sowmya, Udensi, Uchechukwu, Asomugha, Chinwe, Bohat, Ritu, Gallegos, Juan J., Seavitt, John R., Heaney, Jason D., Beaudet, Arthur L., Dickinson, Mary E., Justice, Monica J., Philip, Vivek, Kumar, Vivek, Svenson, Karen L., Braun, Robert E., Wells, Sara, Cater, Heather, Stewart, Michelle, Clementson-Mobbs, Sharon, Joynson, Russell, Gao, Xiang, Suzuki, Tomohiro, Wakana, Shigeharu, Smedley, Damian, Seong, J. K, Tocchini-Valentini, Glauco, Moore, Mark, Fletcher, Colin, Karp, Natasha, Ramirez-Solis, Ramiro, White, Jacqueline K., de Angelis, Martin Hrabe, Wurst, Wolfgang, Thomasy, Sara M., Flicek, Paul, Parkinson, Helen, Brown, Steve D. M., Meehan, Terrence F., Nishina, Patsy M., Murray, Stephen A., Krebs, Mark P., Mallon, Ann-Marie, Lloyd, K. C. Kent, Murphy, Christopher J., Moshiri, Ala
Publicado en Commun Biol (2018)