Proteotyping of knockout mouse strains reveals sex- and strain-specific signatures in blood plasma

We proteotyped blood plasma from 30 mouse knockout strains and corresponding wild-type mice from the International Mouse Phenotyping Consortium. We used targeted proteomics with internal standards to quantify 375 proteins in 218 samples. Our results provide insights into the manifested effects of ea...

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Pubblicato in:NPJ Syst Biol Appl
Autori principali: Mohammed, Yassene, Michaud, Sarah A., Pětrošová, Helena, Yang, Juncong, Ganguly, Milan, Schibli, David, Flenniken, Ann M., Nutter, Lauryl M. J., Adissu, Hibret A., Lloyd, K. C. Kent, McKerlie, Colin, Borchers, Christoph H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8163790/
https://ncbi.nlm.nih.gov/pubmed/34050187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41540-021-00184-8
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