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Src homology 2 domain–containing inositol 5-phosphatase 1 deficiency leads to a spontaneous allergic inflammation in the murine lung
BACKGROUND: Src homology 2 domain–containing inositol 5-phosphatase 1 (SHIP-1) controls the intracellular level of the phosphoinositide 3–kinase product phosphotidylinositol-3,4,5-trisphosphate and functions as a negative regulator of cytokine and immune receptor signaling. Emerging evidence suggest...
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| Udgivet i: | J Allergy Clin Immunol |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4757810/ https://ncbi.nlm.nih.gov/pubmed/17208593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2006.08.029 |
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