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src homology 2 domain–containing tyrosine phosphatase SHP-1 controls the development of allergic airway inflammation

Th2 cells are generated from naive CD4 T cells upon T cell receptor (TCR) recognition of antigen and IL-4 stimulation and play crucial roles in humoral immunity against infectious microorganisms and the pathogenesis of allergic and autoimmune diseases. A tyrosine phosphatase, SHP-1, that contains sr...

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Autors principals: Kamata, Tohru, Yamashita, Masakatsu, Kimura, Motoko, Murata, Kaoru, Inami, Masamichi, Shimizu, Chiori, Sugaya, Kaoru, Wang, Chrong-Reen, Taniguchi, Masaru, Nakayama, Toshinori
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC151831/
https://ncbi.nlm.nih.gov/pubmed/12511594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200315719
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