The src homology 2-containing inositol phosphatase (SHIP) is the gatekeeper of mast cell degranulation

To clarify the role that the src homology 2-containing inositol phosphatase (SHIP) plays in mast cell degranulation, the gene for SHIP was disrupted by homologous recombination in embryonic stem cells. Bone-marrow-derived mast cells from SHIP+/+, +/−, and −/− F(2) littermates were compared. SHIP−/−...

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Autores principales: Huber, Michael, Helgason, Cheryl D., Damen, Jacqueline E., Liu, Ling, Humphries, R. Keith, Krystal, Gerald
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 1998
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC21642/
https://ncbi.nlm.nih.gov/pubmed/9736736
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