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The src homology 2-containing inositol phosphatase (SHIP) is the gatekeeper of mast cell degranulation

To clarify the role that the src homology 2-containing inositol phosphatase (SHIP) plays in mast cell degranulation, the gene for SHIP was disrupted by homologous recombination in embryonic stem cells. Bone-marrow-derived mast cells from SHIP+/+, +/−, and −/− F(2) littermates were compared. SHIP−/−...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Huber, Michael, Helgason, Cheryl D., Damen, Jacqueline E., Liu, Ling, Humphries, R. Keith, Krystal, Gerald
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1998
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21642/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9736736/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.19.11330
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