Src homology 2 domain–containing inositol 5-phosphatase 1 deficiency leads to a spontaneous allergic inflammation in the murine lung

BACKGROUND: Src homology 2 domain–containing inositol 5-phosphatase 1 (SHIP-1) controls the intracellular level of the phosphoinositide 3–kinase product phosphotidylinositol-3,4,5-trisphosphate and functions as a negative regulator of cytokine and immune receptor signaling. Emerging evidence suggest...

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Oh, Sun-Young, Zheng, Tao, Bailey, Monica L., Barber, Dwayne L., Schroeder, John T., Kim, Yoon-Keun, Zhu, Zhou
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4757810/
https://ncbi.nlm.nih.gov/pubmed/17208593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2006.08.029
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