Building a better understanding of the intracellular tyrosine kinase PTK6 – BRK by BRK

Por Brauer, Patrick M., Tyner, Angela L.
Publicado em 2010

RAKing in AKT: A Tumor Suppressor Function for the Intracellular Tyrosine Kinase FRK

Por Brauer, Patrick M., Tyner, Angela L.
Publicado em 2009

Cytoplasmic retention of protein tyrosine kinase 6 promotes growth of prostate tumor cells

Por Brauer, Patrick M, Zheng, Yu, Wang, Lin, Tyner, Angela L
Publicado em 2010

T Cell Genesis: In Vitro Veritas Est?

Por Brauer, Patrick M., Singh, Jastaranpreet, Xhiku, Sintia, Zúñiga-Pflücker, Juan Carlos
Publicado no Trends Immunol (2016)

ARF stimulates XPC to trigger nucleotide excision repair by regulating the repressor complex of E2F4

Por Dominguez-Brauer, Carmen, Chen, Yi-Ju, Brauer, Patrick M, Pimkina, Julia, Raychaudhuri, Pradip
Publicado em 2009

The Alternative Splice Variant of Protein Tyrosine Kinase 6 Negatively Regulates Growth and Enhances PTK6-Mediated Inhibition of β-Catenin

Por Brauer, Patrick M., Zheng, Yu, Evans, Mark D., Dominguez-Brauer, Carmen, Peehl, Donna M., Tyner, Angela L.
Publicado em 2011

Identification of β-catenin as a target of the intracellular tyrosine kinase PTK6

Por Palka-Hamblin, Helena L., Gierut, Jessica J., Bie, Wenjun, Brauer, Patrick M., Zheng, Yu, Asara, John M., Tyner, Angela L.
Publicado em 2010

High-content screening identifies kinase inhibitors that overcome venetoclax resistance in activated CLL cells

Por Oppermann, Sina, Ylanko, Jarkko, Shi, Yonghong, Hariharan, Santosh, Oakes, Christopher C., Brauer, Patrick M., Zúñiga-Pflücker, Juan C., Leber, Brian, Spaner, David E., Andrews, David W.
Publicado no Blood (2016)

The Role of Induced Pluripotent Stem Cells in Research and Therapy of Primary Immunodeficiencies

Por Weinacht, Katja G., Brauer, Patrick M., Felgentreff, Kerstin, Devine, Alex, Gennery, Andrew R., Giliani, Silvia, Al-Herz, Waleed, Schambach, Axel, Zúñiga-Pflücker, Juan Carlos, Notarangelo, Luigi D.
Publicado em 2012

PTK6 activation at the membrane regulates epithelial-mesenchymal transition in prostate cancer

Por Zheng, Yu, Wang, Zebin, Bie, Wenjun, Brauer, Patrick M., White, Bethany E. Perez, Li, Jing, Nogueira, Veronique, Raychaudhuri, Pradip, Hay, Nissim, Tonetti, Debra A., Macias, Virgilia, Kajdacsy-Balla, André, Tyner, Angela L.
Publicado em 2013

Modeling altered T-cell development with induced pluripotent stem cells from patients with RAG1-dependent immune deficiencies

Por Brauer, Patrick M., Pessach, Itai M., Clarke, Erik, Rowe, Jared H., Ott de Bruin, Lisa, Lee, Yu Nee, Dominguez-Brauer, Carmen, Comeau, Anne M., Awong, Geneve, Felgentreff, Kerstin, Zhang, Yuhang H., Bredemeyer, Andrea, Al-Herz, Waleed, Du, Likun, Ververs, Francesca, Kennedy, Marion, Giliani, Silvia, Keller, Gordon, Sleckman, Barry P., Schatz, David G., Bushman, Frederic D., Notarangelo, Luigi D., Zúñiga-Pflücker, Juan Carlos
Publicado no Blood (2016)

Mule Regulates the Intestinal Stem Cell Niche via the Wnt Pathway and Targets EphB3 for Proteasomal and Lysosomal Degradation

Por Dominguez-Brauer, Carmen, Hao, Zhenyue, Elia, Andrew J., Fortin, Jérôme M., Nechanitzky, Robert, Brauer, Patrick M., Sheng, Yi, Mana, Miyeko D., Chio, Iok In Christine, Haight, Jillian, Pollett, Aaron, Cairns, Robert, Tworzyanski, Leanne, Inoue, Satoshi, Reardon, Colin, Marques, Ana, Silvester, Jennifer, Cox, Maureen A., Wakeham, Andrew, Yilmaz, Omer H., Sabatini, David M., van Es, Johan H., Clevers, Hans, Sato, Toshiro, Mak, Tak W.
Publicado no Cell Stem Cell (2016)

EXTL3 mutations cause skeletal dysplasia, immune deficiency, and developmental delay

Por Volpi, Stefano, Yamazaki, Yasuhiro, Brauer, Patrick M., van Rooijen, Ellen, Hayashida, Atsuko, Slavotinek, Anne, Sun Kuehn, Hye, Di Rocco, Maja, Rivolta, Carlo, Bortolomai, Ileana, Du, Likun, Felgentreff, Kerstin, Ott de Bruin, Lisa, Hayashida, Kazutaka, Freedman, George, Marcovecchio, Genni Enza, Capuder, Kelly, Rath, Prisni, Luche, Nicole, Hagedorn, Elliott J., Buoncompagni, Antonella, Royer-Bertrand, Beryl, Giliani, Silvia, Poliani, Pietro Luigi, Imberti, Luisa, Dobbs, Kerry, Poulain, Fabienne E., Martini, Alberto, Manis, John, Linhardt, Robert J., Bosticardo, Marita, Rosenzweig, Sergio Damian, Lee, Hane, Puck, Jennifer M., Zúñiga-Pflücker, Juan Carlos, Zon, Leonard, Park, Pyong Woo, Superti-Furga, Andrea, Notarangelo, Luigi D.
Publicado no J Exp Med (2017)