RAG deficiencies: Recent advances in disease pathogenesis and novel therapeutic approaches

por Bosticardo, Marita, Pala, Francesca, Notarangelo, Luigi D.
Publicado en Eur J Immunol (2021)

Autoimmunity in Wiskott–Aldrich Syndrome: An Unsolved Enigma

por Catucci, Marco, Castiello, Maria Carmina, Pala, Francesca, Bosticardo, Marita, Villa, Anna
Publicado 2012

Self-inactivating Retroviral Vector-mediated Gene Transfer Induces Oncogene Activation and Immortalization of Primary Murine Bone Marrow Cells

por Bosticardo, Marita, Ghosh, Amrita, Du, Yang, Jenkins, Nancy A, Copeland, Neal G, Candotti, Fabio
Publicado 2009

Development of Central Nervous System Autoimmunity Is Impaired in the Absence of Wiskott-Aldrich Syndrome Protein

por Bosticardo, Marita, Musio, Silvia, Fontana, Elena, Angiari, Stefano, Draghici, Elena, Constantin, Gabriela, Poliani, Pietro L., Pedotti, Rosetta, Villa, Anna
Publicado 2014

Gut Microbiota–Host Interactions in Inborn Errors of Immunity

por Castagnoli, Riccardo, Pala, Francesca, Bosticardo, Marita, Licari, Amelia, Delmonte, Ottavia M., Villa, Anna, Marseglia, Gian Luigi, Notarangelo, Luigi Daniele
Publicado en Int J Mol Sci (2021)

Dendritic cell functional improvement in a preclinical model of lentiviral-mediated gene therapy for Wiskott-Aldrich syndrome

por Catucci, Marco, Prete, Francesca, Bosticardo, Marita, Castiello, Maria Carmina, Draghici, Elena, Locci, Michela, Roncarolo, Maria Grazia, Aiuti, Alessandro, Benvenuti, Federica, Villa, Anna
Publicado 2011

Phosphate Transporter Profiles in Murine and Human Thymi Identify Thymocytes at Distinct Stages of Differentiation

por Machado, Alice, Pouzolles, Marie, Gailhac, Sarah, Fritz, Vanessa, Craveiro, Marco, López-Sánchez, Uriel, Kondo, Taisuke, Pala, Francesca, Bosticardo, Marita, Notarangelo, Luigi D., Petit, Vincent, Taylor, Naomi, Zimmermann, Valérie S.
Publicado en Front Immunol (2020)

Lentiviral-mediated gene therapy restores B cell tolerance in Wiskott-Aldrich syndrome patients

por Pala, Francesca, Morbach, Henner, Castiello, Maria Carmina, Schickel, Jean-Nicolas, Scaramuzza, Samantha, Chamberlain, Nicolas, Cassani, Barbara, Glauzy, Salome, Romberg, Neil, Candotti, Fabio, Aiuti, Alessandro, Bosticardo, Marita, Villa, Anna, Meffre, Eric
Publicado en J Clin Invest (2015)

Autonomous role of Wiskott-Aldrich syndrome platelet deficiency in inducing autoimmunity and inflammation

por Sereni, Lucia, Castiello, Maria Carmina, Marangoni, Francesco, Anselmo, Achille, di Silvestre, Dario, Motta, Sara, Draghici, Elena, Mantero, Stefano, Thrasher, Adrian J., Giliani, Silvia, Aiuti, Alessandro, Mauri, Pierluigi, Notarangelo, Luigi D., Bosticardo, Marita, Villa, Anna
Publicado en J Allergy Clin Immunol (2018)

Adult onset myopathy in a patient with hypomorphic RAG2 mutations and combined immune deficiency

por Henrickson, Sarah E., Walter, Jolan E., Quinn, Colin, Kanakry, Jennifer A., Bardakjian, Tanya, Dimitrova, Dimana, Ujhazi, Boglarka, Csomos, Krisztian, Bosticardo, Marita, Dobbs, Kerry, Nasrallah, MacLean, Notarangelo, Luigi D., Holland, Steven M., Fadugba, Olajumoke
Publicado en J Clin Immunol (2018)

B-cell reconstitution after lentiviral vector–mediated gene therapy in patients with Wiskott-Aldrich syndrome

por Castiello, Maria Carmina, Scaramuzza, Samantha, Pala, Francesca, Ferrua, Francesca, Uva, Paolo, Brigida, Immacolata, Sereni, Lucia, van der Burg, Mirjam, Ottaviano, Giorgio, Albert, Michael H., Grazia Roncarolo, Maria, Naldini, Luigi, Aiuti, Alessandro, Villa, Anna, Bosticardo, Marita
Publicado en J Allergy Clin Immunol (2015)

Neutrophils drive type I interferon production and autoantibodies in patients with Wiskott-Aldrich syndrome

por Cervantes-Luevano, Karla E., Caronni, Nicoletta, Castiello, Maria C., Fontana, Elena, Piperno, Giulia M., Naseem, Asma, Uva, Paolo, Bosticardo, Marita, Marcovecchio, Genni E., Notarangelo, Luigi D., Cicalese, Maria P., Aiuti, Alessandro, Villa, Anna, Benvenuti, Federica
Publicado en J Allergy Clin Immunol (2018)

Efficacy and safety of anti-CD45–saporin as conditioning agent for RAG deficiency

por Castiello, Maria Carmina, Bosticardo, Marita, Sacchetti, Nicolò, Calzoni, Enrica, Fontana, Elena, Yamazaki, Yasuhiro, Draghici, Elena, Corsino, Cristina, Bortolomai, Ileana, Sereni, Lucia, Yu, Hsin-Hui, Uva, Paolo, Palchaudhuri, Rahul, Scadden, David T., Villa, Anna, Notarangelo, Luigi D.
Publicado en J Allergy Clin Immunol (2020)

The Wiskott-Aldrich syndrome protein is required for iNKT cell maturation and function

por Locci, Michela, Draghici, Elena, Marangoni, Francesco, Bosticardo, Marita, Catucci, Marco, Aiuti, Alessandro, Cancrini, Caterina, Marodi, Laszlo, Espanol, Teresa, Bredius, Robbert G.M., Thrasher, Adrian J., Schulz, Ansgar, Litzman, Jiri, Roncarolo, Maria Grazia, Casorati, Giulia, Dellabona, Paolo, Villa, Anna
Publicado 2009

A hypomorphic R229Q Rag2 mouse mutant recapitulates human Omenn syndrome

por Marrella, Veronica, Poliani, Pietro Luigi, Casati, Anna, Rucci, Francesca, Frascoli, Laura, Gougeon, Marie-Lise, Lemercier, Brigitte, Bosticardo, Marita, Ravanini, Maria, Battaglia, Manuela, Roncarolo, Maria Grazia, Cavazzana-Calvo, Marina, Facchetti, Fabio, Notarangelo, Luigi D., Vezzoni, Paolo, Grassi, Fabio, Villa, Anna
Publicado 2007

Wiskott–Aldrich Syndrome protein deficiency perturbs the homeostasis of B-cell compartment in humans()

por Castiello, Maria Carmina, Bosticardo, Marita, Pala, Francesca, Catucci, Marco, Chamberlain, Nicolas, van Zelm, Menno C., Driessen, Gertjan J., Pac, Malgorzata, Bernatowska, Ewa, Scaramuzza, Samantha, Aiuti, Alessandro, Sauer, Aisha V., Traggiai, Elisabetta, Meffre, Eric, Villa, Anna, van der Burg, Mirjam
Publicado 2014

In Vivo Chronic Stimulation Unveils Autoreactive Potential of Wiskott–Aldrich Syndrome Protein-Deficient B Cells

por Castiello, Maria Carmina, Pala, Francesca, Sereni, Lucia, Draghici, Elena, Inverso, Donato, Sauer, Aisha V., Schena, Francesca, Fontana, Elena, Radaelli, Enrico, Uva, Paolo, Cervantes-Luevano, Karla E., Benvenuti, Federica, Poliani, Pietro L., Iannacone, Matteo, Traggiai, Elisabetta, Villa, Anna, Bosticardo, Marita
Publicado en Front Immunol (2017)

Corrigendum to “Evidence for Long-term Efficacy and Safety of Gene Therapy for Wiskott–Aldrich Syndrome in Preclinical Models”

por Marangoni, Francesco, Bosticardo, Marita, Charrier, Sabine, Draghici, Elena, Locci, Michela, Scaramuzza, Samantha, Panaroni, Cristina, Ponzoni, Maurilio, Sanvito, Francesca, Doglioni, Claudio, Liabeuf, Marie, Gjata, Bernard, Montus, Marie, Siminovitch, Katherine, Aiuti, Alessandro, Naldini, Luigi, Dupré, Loïc, Roncarolo, Maria Grazia, Galy, Anne, Villa, Anna
Publicado 2009

Evidence for Long-term Efficacy and Safety of Gene Therapy for Wiskott–Aldrich Syndrome in Preclinical Models

por Marangoni, Francesco, Bosticardo, Marita, Charrier, Sabine, Draghici, Elena, Locci, Michela, Scaramuzza, Samantha, Panaroni, Cristina, Ponzoni, Maurilio, Sanvito, Francesca, Doglioni, Claudio, Liabeuf, Marie, Gjata, Bernard, Montus, Marie, Siminovitch, Katherine, Aiuti, Alessandro, Naldini, Luigi, Dupré, Loïc, Roncarolo, Maria Grazia, Galy, Anne, Villa, Anna
Publicado 2009

Premature Senescence and Increased Oxidative Stress in the Thymus of Down Syndrome Patients

por Marcovecchio, Genni Enza, Ferrua, Francesca, Fontana, Elena, Beretta, Stefano, Genua, Marco, Bortolomai, Ileana, Conti, Anastasia, Montin, Davide, Cascarano, Maria Teresa, Bergante, Sonia, D’Oria, Veronica, Giamberti, Alessandro, Amodio, Donato, Cancrini, Caterina, Carotti, Adriano, Di Micco, Raffaella, Merelli, Ivan, Bosticardo, Marita, Villa, Anna
Publicado en Front Immunol (2021)