CD19 controls TLR9 responses in human B cells

Por Morbach, Henner, Schickel, Jean-Nicolas, Cunningham-Rundles, Charlotte, Conley, Mary Ellen, Reisli, Ismail, Franco, Jose Luis, Meffre, Eric
Publicado no J Allergy Clin Immunol (2015)

The V gene repertoires of classical and atypical memory B cells in malaria-susceptible West African children()

Por Zinöcker, Severin, Schindler, Christine E., Skinner, Jeff, Rogosch, Tobias, Waisberg, Michael, Schickel, Jean-Nicolas, Meffre, Eric, Kayentao, Kassoum, Ongoïba, Aïssata, Traoré, Boubacar, Pierce, Susan K.
Publicado no J Immunol (2015)

Circulating human CD27-IgA+ memory-B cells recognize bacteria with polyreactive immunoglobulins()

Por Berkowska, Magdalena A., Schickel, Jean-Nicolas, Grosserichter-Wagener, Christina, de Ridder, Dick, Ng, Yen Shing, van Dongen, Jacques J.M., Meffre, Eric, van Zelm, Menno C.
Publicado no J Immunol (2015)

B Cell Signature during Inactive Systemic Lupus Is Heterogeneous: Toward a Biological Dissection of Lupus

Por Garaud, Jean-Claude, Schickel, Jean-Nicolas, Blaison, Gilles, Knapp, Anne-Marie, Dembele, Doulaye, Ruer-Laventie, Julie, Korganow, Anne-Sophie, Martin, Thierry, Soulas-Sprauel, Pauline, Pasquali, Jean-Louis
Publicado em 2011

Molecular dissection of human b-cell tolerance - insights from primary immunodeficiencies

Por Morbach, Henner, Meyers, Greta, Ng, Yen-Shing, Schickel, Jean-Nicolas, Menard, Laurence, Rudchenko, Sergei, Rojas, Jessica, Cunningham-Rundles, Charlotte, Conley, Mary, Reisli, Ismail, Franco, Jose, Meffre, Eric
Publicado em 2014

Carabin deficiency in B cells increases BCR-TLR9 costimulation-induced autoimmunity

Por Schickel, Jean-Nicolas, Pasquali, Jean-Louis, Soley, Anne, Knapp, Anne-Marie, Decossas, Marion, Kern, Aurélie, Fauny, Jean-Daniel, Marcellin, Luc, Korganow, Anne-Sophie, Martin, Thierry, Soulas-Sprauel, Pauline
Publicado em 2012

TNFRSF13B hemizygosity reveals TACI haploinsufficiency at later stages of B-cell development

Por Romberg, Neil, Virdee, Manmeet, Chamberlain, Nicolas, Oe, Tyler, Schickel, Jean-Nicolas, Perkins, Tiffany, Cantaert, Tineke, Rachid, Rima, Rosengren, Sally, Palazzo, Regina, Geha, Raif, Cunningham-Rundles, Charlotte, Meffre, Eric
Publicado no J Allergy Clin Immunol (2015)

PTPN22 inhibition resets defective human central B cell tolerance

Por Schickel, Jean-Nicolas, Kuhny, Marcel, Baldo, Alessia, Bannock, Jason M., Massad, Christopher, Wang, Haowei, Katz, Nathan, Oe, Tyler, Menard, Laurence, Soulas-Sprauel, Pauline, Strowig, Till, Flavell, Richard, Meffre, Eric
Publicado no Sci Immunol (2016)

Overexpression of Fkbp11, a feature of lupus B cells, leads to B cell tolerance breakdown and initiates plasma cell differentiation

Por Ruer-Laventie, Julie, Simoni, Léa, Schickel, Jean-Nicolas, Soley, Anne, Duval, Monique, Knapp, Anne-Marie, Marcellin, Luc, Lamon, Delphine, Korganow, Anne-Sophie, Martin, Thierry, Pasquali, Jean-Louis, Soulas-Sprauel, Pauline
Publicado no Immun Inflamm Dis (2015)

Lentiviral-mediated gene therapy restores B cell tolerance in Wiskott-Aldrich syndrome patients

Por Pala, Francesca, Morbach, Henner, Castiello, Maria Carmina, Schickel, Jean-Nicolas, Scaramuzza, Samantha, Chamberlain, Nicolas, Cassani, Barbara, Glauzy, Salome, Romberg, Neil, Candotti, Fabio, Aiuti, Alessandro, Bosticardo, Marita, Villa, Anna, Meffre, Eric
Publicado no J Clin Invest (2015)

Molecular dissection of human B-cell tolerance – insights from patients with rare genetic diseases

Por Morbach, Henner, Meyers, Greta, Ng, Yen-Shing, Schickel, Jean-Nicolas, Menard, Laurence, Rudchenko, Sergei, Rojas, Jessica L, Cunningham-Rundles, Charlotte, Conley, Mary Ellen, Reisli, Ismail, Franco, Jose Luis, Meffre, Eric
Publicado no Mol Cell Pediatr (2014)

A novel humanized mouse model with significant improvement of class-switched, antigen-specific antibody production

Por Yu, Hua, Borsotti, Chiara, Schickel, Jean-Nicolas, Zhu, Shu, Strowig, Till, Eynon, Elizabeth E., Frleta, Davor, Gurer, Cagan, Murphy, Andrew J., Yancopoulos, George D., Meffre, Eric, Manz, Markus G., Flavell, Richard A.
Publicado no Blood (2017)

Activation-induced cytidine deaminase (AID) expression in human B-cell precursors is essential for central B-cell tolerance

Por Cantaert, Tineke, Schickel, Jean-Nicolas, Bannock, Jason M., Ng, Yen-Shing, Massad, Christopher, Oe, Tyler, Wu, Renee, Lavoie, Aubert, Walter, Jolan E., Notarangelo, Luigi D., Al-Herz, Waleed, Kilic, Sara Sebnem, Ochs, Hans D., Nonoyama, Shigeaki, Durandy, Anne, Meffre, Eric
Publicado no Immunity (2015)

Decreased somatic hypermutation induces an impaired peripheral B cell tolerance checkpoint

Por Cantaert, Tineke, Schickel, Jean-Nicolas, Bannock, Jason M., Ng, Yen-Shing, Massad, Christopher, Delmotte, Fabien R., Yamakawa, Natsuko, Glauzy, Salome, Chamberlain, Nicolas, Kinnunen, Tuure, Menard, Laurence, Lavoie, Aubert, Walter, Jolan E., Notarangelo, Luigi D., Bruneau, Julie, Al-Herz, Waleed, Kilic, Sara Sebnem, Ochs, Hans D., Cunningham-Rundles, Charlotte, van der Burg, Mirjam, Kuijpers, Taco W., Kracker, Sven, Kaneko, Hideo, Sekinaka, Yujin, Nonoyama, Shigeaki, Durandy, Anne, Meffre, Eric
Publicado no J Clin Invest (2016)

Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4

Por Kuehn, Hye Sun, Ouyang, Weiming, Lo, Bernice, Deenick, Elissa K., Niemela, Julie E., Avery, Danielle T., Schickel, Jean-Nicolas, Tran, Dat Q., Stoddard, Jennifer, Zhang, Yu, Frucht, David M., Dumitriu, Bogdan, Scheinberg, Phillip, Folio, Les R., Frein, Cathleen A., Price, Susan, Koh, Christopher, Heller, Theo, Seroogy, Christine M., Huttenlocher, Anna, Rao, V. Koneti, Su, Helen C., Kleiner, David, Notarangelo, Luigi D., Rampertaap, Yajesh, Olivier, Kenneth N., McElwee, Joshua, Hughes, Jason, Pittaluga, Stefania, Oliveira, Joao B., Meffre, Eric, Fleisher, Thomas A., Holland, Steven M., Lenardo, Michael J., Tangye, Stuart G., Uzel, Gulbu
Publicado no Science (2014)