Carabin deficiency in B cells increases BCR-TLR9 costimulation-induced autoimmunity

The mechanisms behind flares of human autoimmune diseases in general, and of systemic lupus in particular, are poorly understood. The present scenario proposes that predisposing gene defects favour clinical flares under the influence of external stimuli. Here, we show that Carabin is low in B cells...

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Detalhes bibliográficos
Main Authors: Schickel, Jean-Nicolas, Pasquali, Jean-Louis, Soley, Anne, Knapp, Anne-Marie, Decossas, Marion, Kern, Aurélie, Fauny, Jean-Daniel, Marcellin, Luc, Korganow, Anne-Sophie, Martin, Thierry, Soulas-Sprauel, Pauline
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531602/
https://ncbi.nlm.nih.gov/pubmed/23109291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201201595
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