B-cell reconstitution after lentiviral vector–mediated gene therapy in patients with Wiskott-Aldrich syndrome

BACKGROUND: Wiskott-Aldrich syndrome (WAS) is a severe X-linked immunodeficiency characterized by microthrombocytopenia, eczema, recurrent infections, and susceptibility to autoimmunity and lymphomas. Hematopoietic stem cell transplantation is the treatment of choice; however, administration of WAS...

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Bibliografski detalji
Izdano u:J Allergy Clin Immunol
Glavni autori: Castiello, Maria Carmina, Scaramuzza, Samantha, Pala, Francesca, Ferrua, Francesca, Uva, Paolo, Brigida, Immacolata, Sereni, Lucia, van der Burg, Mirjam, Ottaviano, Giorgio, Albert, Michael H., Grazia Roncarolo, Maria, Naldini, Luigi, Aiuti, Alessandro, Villa, Anna, Bosticardo, Marita
Format: Artigo
Jezik:Inglês
Izdano: Mosby 2015
Teme:
Immune Deficiencies, Infection, and Systemic Immune Disorders
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559137/
https://ncbi.nlm.nih.gov/pubmed/25792466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2015.01.035
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