B-cell reconstitution after lentiviral vector–mediated gene therapy in patients with Wiskott-Aldrich syndrome

BACKGROUND: Wiskott-Aldrich syndrome (WAS) is a severe X-linked immunodeficiency characterized by microthrombocytopenia, eczema, recurrent infections, and susceptibility to autoimmunity and lymphomas. Hematopoietic stem cell transplantation is the treatment of choice; however, administration of WAS...

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Castiello, Maria Carmina, Scaramuzza, Samantha, Pala, Francesca, Ferrua, Francesca, Uva, Paolo, Brigida, Immacolata, Sereni, Lucia, van der Burg, Mirjam, Ottaviano, Giorgio, Albert, Michael H., Grazia Roncarolo, Maria, Naldini, Luigi, Aiuti, Alessandro, Villa, Anna, Bosticardo, Marita
Formato: Artigo
Idioma:Inglês
Publicado em: Mosby 2015
Assuntos:
Immune Deficiencies, Infection, and Systemic Immune Disorders
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559137/
https://ncbi.nlm.nih.gov/pubmed/25792466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2015.01.035
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